Vitreous Changes After Cataract Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses spectral-domain OCT imaging to compare preoperative and postoperative vitreous and vitreoretinal interface features in patients undergoing cataract surgery. Standardized OCT protocols (18 Line R64 and AS Star 18 Line R16 on the Dream OCT platform) will be used to assess changes in the posterior vitreous, its attachment to the retinal surface, and any alterations after surgery. Qualitative and quantitative analyses will identify the visibility, configuration, position, and attachment of posterior vitreous structures, aiming to characterize postoperative vitreous modifications. Eligible participants must have high-quality OCT images and no baseline PVD, with both pre- and post-surgery scans available for comparison.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Presence of cataract scheduled for surgery
* Adequate image acquisition quality
* Absence of posterior vitreous detachment (PVD)
* Availability of both preoperative and postoperative OCT imaging

Exclusion Criteria:

* Advanced cataract significantly compromising image quality
* Presence of posterior vitreous detachment (PVD)

  * History of vitreous hemorrhage
  * Previous vitreoretinal surgery
  * Previous intravitreal injections (IVT)
  * Retinal diseases affecting vitreoretinal interface assessment
  * Pathologic high myopia
  * History of ocular trauma or uveitis

Where it's running

• Centre Hospitalier Intercommunal de Créteil
  Créteil, Paris, France Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Neuroplastic pain education and guided breathing during awake cataract surgery

  This trial tests whether the STEIN Protocol, a non-drug approach with pain education, guided imagery, and paced breathing, helps adults having cataract surgery require less pain medicine and feel less anxious.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07715591

• Bilateral Implantation of enVista Envy Trifocal IOL for Cataract Patients

  This study tests whether the enVista Envy trifocal intraocular lens can provide good distance, intermediate, and near vision after cataract surgery in adults who want less dependence on glasses.

  Recruiting Pomeranian Medical University Szczecin · Szczecin, Zachodnipomorskie · NCT07696130

• Trying mirtazapine to help symptoms of Rett syndrome

  This trial will try mirtazapine, an antidepressant, to see if it improves mood, sleep, breathing problems, and hand control in girls and women aged 5–40 with Rett syndrome and a confirmed MECP2 mutation.

  Recruiting at 4 sites Phase 2 University of Trieste · Genova and 3 other locations · NCT07430046

• Shoulder-focused versus whole-body physiotherapy for volleyball players with shoulder pain

  We will test whether shoulder-focused or whole-body physiotherapy helps volleyball players with shoulder pain more than education alone.

  Recruiting University of Trieste · Trieste, Trieste · NCT07072091

• At-home cortico-spinal tDCS for ALS.

  This treatment tests whether daily at-home cortico-spinal tDCS can slow nerve damage and symptoms in adults with early ALS.

  Recruiting University of Trieste · Trieste, Trieste · NCT07006571

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.