Vitamin D supplementation for premature infants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effects of vitamin D supplementation at 800 IU/day against usual care in extremely premature infants for the first 28 days after birth. It focuses on measuring vitamin D levels and assessing potential impacts on lung, bone, immune system, and brain function. The study will utilize intention-to-treat Bayesian analyses, along with Frequentist analyses, to evaluate the outcomes. The target population includes infants born at less than 28 weeks gestational age or weighing less than 1000 grams.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infants born at \< 28 weeks gestational age (GA) or \<1000 grams birth weight (BW)
* Inborn
* Informed written consent in an Institutional Review Board (IRB)-approved manner

Exclusion Criteria:

* GA \>32 weeks regardless of birth weight (BW)
* Any major congenital anomaly
* A known congenital nonbacterial infection
* Prenatal diagnosis of disorders that affect vitamin D absorption (e.g, cystic fibrosis)
* Such severe illness or immaturity that the attending neonatologist judges intensive care to be unjustified.

Where it's running

• The University of Texas Health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Maria del Mar Romero López, MD — The University of Texas Health Science Center, Houston
• Study coordinator: Maria del Mar Romero López, MD
• Email: Maria.del.Mar.RomeroLopez@uth.tmc.edu
• Phone: 713-500-7283

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Vitamin D2 with Calcitriol in kids with cholestasis and vitamin D deficiency

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  Recruiting Phase 4 Chulalongkorn University · Bangkok · NCT07670611

• Vitamin D and the body's anti-inflammatory response in gum disease

  This study tests whether vitamin D can modulate the body's anti-inflammatory response in people with gum disease.

  Recruiting Recep Tayyip Erdogan University Training and Research Hospital · Rize · NCT07636733

• Bone Myoregulation and Posture in Vitamin D Deficiency

  This observational study tests whether adults with vitamin D deficiency differ in postural stability and muscle activity from healthy controls during a single-session, noninvasive assessment.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul · NCT07435935

• Adding exercise to vitamin D treatment for diabetic men with erectile dysfunction and low vitamin D.

  This trial will see if adding regular moderate treadmill walking to high‑dose vitamin D replacement helps men with type 2 diabetes, chronic erectile dysfunction, and low vitamin D levels.

  Recruiting Cairo University · Dokki, Giza Governorate · NCT07366970

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.