Clinical trial Recruiting at 2 sites Interventional Ages 40 to 80

Visual feedback from the SpiroGym app for breathing training in Parkinson's

Official title: The Effect of Visual Feedback From the SpiroGym Mobile Application on Expiratory Muscle Strength Training Performance in Patients With Parkinson's Disease

Run by General University Hospital, Prague · NCT06942533 · Data updated 2026-11-12

This study will test whether real-time visual feedback from the SpiroGym app helps people with Parkinson's improve strength and performance during expiratory breathing exercises.

Quick facts

Study typeInterventional
Ages40 Years to 80 Years
SexAll
Enrollment30 (estimated)
SponsorGeneral University Hospital, Prague
Academic / other
Locations2 sites (Prague and 1 other locations)
StatusRecruiting
StartedMay 1, 2025
Main results expectedMay 1, 2026
Study endsJuly 1, 2026
Registry record updatedDecember 1, 2025
Trial IDNCT06942533 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People with a diagnosis of Parkinson's disease who are on a stable dose of dopaminergic medication and who do not have major cognitive, psychiatric, or other neurological disorders are ideal candidates.

Probably not a fit

Patients with significant cognitive impairment, other neurological disorders, unstable dopaminergic treatment, or a history of head or neck cancer or surgery are unlikely to qualify or benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized crossover study has participants with Parkinson's disease complete two expiratory muscle strength training (EMST) sessions at 75% of their maximum expiratory pressure, with a two-week interval between sessions. One session uses the SpiroGym mobile app to provide real-time visual feedback and the other session is performed without the app, with the order randomized. Outcomes include muscle activation measured by surface electromyography (sEMG), noise intensity recorded by SpiroGym as a proxy for expiratory performance, and participant-reported perceived difficulty and motivation. The design tests whether immediate visual feedback changes physiological effort and subjective experience during EMST.

Why it matters

Potential benefit: If successful, adding SpiroGym's visual feedback could make breathing exercises more effective and motivating, potentially improving cough strength and airway protection for people with Parkinson's.

How similar studies have gone: Prior pilot EMST work, including with SpiroGym, has shown rapid improvements in cough-related measures, but the specific added benefit of real-time visual feedback remains unproven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of Parkinsons disease
* Stable dopaminergic medication (stable dose for at least 1 month)

Exclusion Criteria:

* Other neurological disorders
* Significant cognitive impairment
* Major psychiatric disorder
* History of head or neck cancer or previous surgical interventions in the neck region.
* Illness during the study period

Where it's running

  • General University Hospital
    Prague, Czechia
    Recruiting
  • Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague
    Prague, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.