Visual exercises to improve attention in mild cognitive impairment
Effet d'Exercices Visuels de Stimulation Cognitive Sur Les capacités Attentionnelles Chez la Personne âgée (Etude Pilote)
This project tries to see if daily computer-based visual exercises (Emeraude®) for 30 days can speed up information processing in people aged 60 and over with dysexecutive mild cognitive impairment compared with watching television.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | University Hospital, Angers Government |
| Locations | 1 site (Angers) |
| Trial ID | NCT05791994 on ClinicalTrials.gov |
What this trial studies
Participants with dysexecutive mild cognitive impairment will perform either daily adapted visual cognitive exercises using the Emeraude® software or daily viewing of a television program without cognitive stimulation for 30 days. The primary outcome is change in information processing speed after the 30-day intervention, with secondary outcomes including subtest processing speeds, overall cognitive performance, executive functions, walking performance, and quality of life. Eligible participants are aged 60 or older, have an informal caregiver, and meet dysexecutive or multidomain dysexecutive MCI criteria; key exclusions include severe depressive symptoms, vision or central pathology affecting stimulation, anticonvulsant or certain psychotropic use, confusional states, and legal or psychiatric restrictions. Assessments are conducted before and after the intervention to compare change between the two groups.
Who should consider this trial
Good fit: Adults aged 60 or older with dysexecutive or multidomain dysexecutive mild cognitive impairment who have an informal caregiver and can complete daily computer-based visual exercises are ideal candidates.
Not a fit: Individuals with severe depressive symptoms, significant ophthalmological or central pathologies affecting vision, confusional syndrome, regular use of anticonvulsants or certain psychotropic drugs, or those unable to consent are unlikely to benefit or are excluded.
Why it matters
Potential benefit: If effective, these visual cognitive exercises could improve processing speed, executive function, walking, and quality of life for people with dysexecutive MCI.
How similar studies have performed: Previous work in non-demented older adults showed that regular computer-assisted visual exercises improved information processing speed and walking, but this approach is less well studied specifically in dysexecutive MCI.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 60 years * Diagnosis of mild cognitive impairment of a dysexecutive or multidomain dysexecutive nature, according to Winblad consensus criteria * Presence of an informal caregiver * Subject gave and signed informed consent to participate in the study * Affiliation to a social security scheme Exclusion Criteria: * Presence of severe depressive symptoms (4-item Geriatric Depression Scale score \> 2) * Ophthalmological or central pathology that may affect the performance of stimulation exercises * Regular use of psychotropic drugs that may have an impact on the performance of stimulation exercises, in the opinion of the investigator (benzodiazepines, antidepressants, neuroleptics, hypnotics) * Use of anticonvulsant drugs * Existence of a confusional syndrome * Participation in another simultaneous clinical trial * Person deprived of liberty by judicial or administrative decision * Person under forced psychiatric care * Person subject to a legal protection measure * Person unable to give consent
Where this trial is running
Angers
- Angers University Hospital — Angers, France (Recruiting)
Study contacts
- Study coordinator: Marine ASFAR, MD
- Email: marine.asfar@chu-angers.fr
- Phone: +33 2 41 35 47 25
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.