Virtual rehabilitation program for children after hematopoietic cell transplant

A Pilot Study of Virtual Rehabilitation After Hematopoietic Cell Transplantation

Not applicable Interventional Emory University · NCT05943964

This study tests a virtual exercise program for kids aged 8 to 23 recovering from a stem cell transplant to see if it helps them get stronger and feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages8 Years to 23 Years
SexAll
SponsorEmory University Academic / other
Locations1 site (Atlanta, Georgia)
Trial IDNCT05943964 on ClinicalTrials.gov

What this trial studies

This study evaluates the feasibility and effectiveness of a virtual rehabilitation program designed for children aged 8 to 23 years who are recovering from hematopoietic cell transplantation (HCT) and may be experiencing chronic graft-versus-host disease (cGVHD). The program aims to enhance physical fitness and improve quality of life by providing supervised virtual exercise sessions, overcoming barriers such as travel distance and infection risk. Participants will be assessed by a pediatric physical therapist at the start and end of the program to measure improvements in physical functioning and overall well-being. The study seeks to establish a model that could be adopted by other institutions for similar patient populations.

Who should consider this trial

Good fit: Ideal candidates are children aged 8 to 23 years who are at least 100 days post-allogeneic HCT and cleared for exercise by their physician.

Not a fit: Patients with physical impediments to exercise or those who do not speak English may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve physical functioning and quality of life for children recovering from HCT.

How similar studies have performed: While virtual rehabilitation has shown success in cardiac transplant patients, this approach for pediatric HCT patients is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Recipients between the ages of 8 and 23 years ≥100 days post allogeneic HCT.
* Patients 8-14 years old should have a caregiver willing to assist with the implementation of the exercises during the session
* Patients should have access to devices and a reliable internet connection.
* Patients should be cleared for exercise by their physician
* Patients are eligible to participate regardless of underlying diagnosis, preparative regimen, or graft source.

Exclusion Criteria:

* Any physical impediment to exercise as evaluated by the treating physician.
* Non-English-speaking patients (due to a lack of available interpreters through the telemedicine platform).

Where this trial is running

Atlanta, Georgia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hematopoietic Cell TransplantVirtual RehabilitationVirtual ExercisePhysical fitness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.