Virtual Reality Vision Testing for Metamorphopsia and Aniseikonia
Official title: Virtual Reality Aniseikonia and Metamorphopsia Testing
Run by NYU Langone Health · NCT07838181 · Data updated 2026-11-12
A portable virtual reality headset is tested to see if it can more reliably and conveniently measure visual distortions in people with metamorphopsia or aniseikonia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | NYU Langone Health Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | August 4, 2026 |
| Main results expected | June 30, 2028 |
| Study ends | June 30, 2030 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT07838181 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with or without visual distortions who have a history of ERM, AMD, CSR, DME, or CME may participate if they meet imaging and acuity criteria.
✕Probably not a fit
Patients with severe visual impairment or conditions that prevent adequate imaging or testing may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study uses a small, lightweight VR headset to evaluate whether a portable testing platform can reduce confounding factors present in traditional tests. The goal is to provide a contained, accessible environment that minimizes external stimuli and image-filtering effects while measuring distortions in both eyes. Participants include adults with or without visual distortions and with suitable ocular histories, and ophthalmology staff may participate as providers. The study is conducted at NYU Langone Health. The Aegenta VR device is used for testing.
Why it matters
Potential benefit: If successful, the VR-based testing could offer a more practical and consistent way to assess metamorphopsia and aniseikonia in clinical settings.
How similar studies have gone: Previous approaches show promise with VR-based testing, but this exact portable setup is relatively novel for these conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Over 18 years of age * Have no reported visual distortions with a negative Amsler test; or * Have visual distortions with a positive Amsler grid test and an ocular history of one of the following: epiretinal membrane (ERM), age-related Macular degeneration (AMD), central serous retinopathy (CSR), diabetic macular edema (DME), cystoid macular edema (CME) * Ophthalmology residents, staff, and physicians Exclusion Criteria: * Eye pathology limiting view to the posterior pole to obtain adequate quality fundus photograph or OCT imaging in either eye * Impaired visual acuity with best-corrected visual acuity equal to or worse than 20/70 * Motor deficits of the upper extremities
Where it's running
-
NYU Langone Health
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Nitish Mehta, MD — NYU Langone Health
- Study coordinator: Nitish Mehta, MD
- Email: Nitish.Mehta@nyulangone.org
- Phone: 212-263-2573
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.