Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Virtual Reality Vision Testing for Metamorphopsia and Aniseikonia

Official title: Virtual Reality Aniseikonia and Metamorphopsia Testing

Run by NYU Langone Health · NCT07838181 · Data updated 2026-11-12

A portable virtual reality headset is tested to see if it can more reliably and conveniently measure visual distortions in people with metamorphopsia or aniseikonia.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorNYU Langone Health
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedAugust 4, 2026
Main results expectedJune 30, 2028
Study endsJune 30, 2030
Registry record updatedSeptember 24, 2026
Trial IDNCT07838181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with or without visual distortions who have a history of ERM, AMD, CSR, DME, or CME may participate if they meet imaging and acuity criteria.

Probably not a fit

Patients with severe visual impairment or conditions that prevent adequate imaging or testing may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses a small, lightweight VR headset to evaluate whether a portable testing platform can reduce confounding factors present in traditional tests. The goal is to provide a contained, accessible environment that minimizes external stimuli and image-filtering effects while measuring distortions in both eyes. Participants include adults with or without visual distortions and with suitable ocular histories, and ophthalmology staff may participate as providers. The study is conducted at NYU Langone Health. The Aegenta VR device is used for testing.

Why it matters

Potential benefit: If successful, the VR-based testing could offer a more practical and consistent way to assess metamorphopsia and aniseikonia in clinical settings.

How similar studies have gone: Previous approaches show promise with VR-based testing, but this exact portable setup is relatively novel for these conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Over 18 years of age
* Have no reported visual distortions with a negative Amsler test; or
* Have visual distortions with a positive Amsler grid test and an ocular history of one of the following: epiretinal membrane (ERM), age-related Macular degeneration (AMD), central serous retinopathy (CSR), diabetic macular edema (DME), cystoid macular edema (CME)
* Ophthalmology residents, staff, and physicians

Exclusion Criteria:

* Eye pathology limiting view to the posterior pole to obtain adequate quality fundus photograph or OCT imaging in either eye
* Impaired visual acuity with best-corrected visual acuity equal to or worse than 20/70
* Motor deficits of the upper extremities

Where it's running

  • NYU Langone Health
    New York, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Medial unloader brace after root repair

    This study tests whether using a medial unloader brace after arthroscopic medial meniscus posterior root repair helps healing and improves knee outcomes.

    Recruiting NYU Langone Health · New York, New York · NCT07909369

  • MAC-STILA: a feasibility test for hip fracture surgery anesthesia

    This trial tests whether combining monitored anesthesia care with soft tissue infiltration using local anesthesia can reduce post-operative delirium in adults 65 and older undergoing hip fracture repair.

    Recruiting NYU Langone Health · Evanston, Illinois and 4 other locations · NCT07897656

  • Osimertinib with Cyclosporine A for EGFR-mutant NSCLC

    This phase II study tests whether adding cyclosporine A to osimertinib helps people with EGFR-mutant metastatic NSCLC who still have detectable tumor DNA in blood.

    Recruiting Phase 2 NYU Langone Health · New York, New York · NCT07874490

  • Histotripsy with chemotherapy and immunotherapy for biliary tract cancer

    This pilot test will see if adding histotripsy to chemoimmunotherapy is safe and feasible for adults with biliary tract cancer.

    Recruiting NYU Langone Health · New York, New York · NCT07853690

  • A look at why Lewy body conditions cause visual hallucinations

    This study tests brain‑imaging in people with Lewy body diseases who do or don’t experience visual hallucinations, and in healthy volunteers, to see how brain networks might create these images.

    Recruiting NYU Langone Health · New York, New York · NCT07849413

  • Home urine testing for people with lupus

    Participants with lupus will try weekly home urine tests in addition to usual care to see if this helps monitor kidney health over a year.

    Recruiting NYU Langone Health · New York, New York · NCT07823478

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.