Virtual reality therapy for managing chronic low back pain

Extended Reality-Assisted Therapy for Chronic Pain Management: Can Immersive Virtual Reality Improve Range of Motion and Disability in Patients With Chronic Low Back Pain?

Not applicable Interventional Institut d'Investigacions Biomèdiques August Pi i Sunyer · NCT06296433

This study is testing if a virtual reality program can help people with chronic low back pain feel better and move more easily compared to just watching videos.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorInstitut d'Investigacions Biomèdiques August Pi i Sunyer Academic / other
Locations1 site (Barcelona)
Trial IDNCT06296433 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of a home-based virtual reality rehabilitation application for patients suffering from chronic low back pain. Participants will be randomly assigned to either a VR treatment group, where they will engage with a prototype VR application featuring educational content, gamified exercises, and relaxation techniques, or a control group that will watch 2D videos. The intervention will last for 20 minutes daily over a period of three weeks, and researchers will assess improvements in pain, daily function, range of motion, and fear of movement using validated outcome measures. The study seeks to determine if the VR application can provide better outcomes compared to passive VR experiences.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18-65 with a diagnosis of chronic low back pain lasting more than 12 weeks.

Not a fit: Patients with specific spinal conditions, recent surgeries, or neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce pain and improve daily functioning for patients with chronic low back pain.

How similar studies have performed: Other studies have shown promise in using virtual reality for pain management, suggesting potential success for this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-65 of either sex
* Diagnosis of chronic low back pain of \>12 weeks, with or without associated somatic referred leg pain
* Average pain intensity over the previous month ≤7/10 and ≥ 2/10)

Exclusion Criteria:

* Spondylolysis, fracture, cauda equina syndrome, active spinal infection
* Acute radiculopathy or compromised nerve root
* Recent spinal surgery (\<12 months) or lower limb surgery (\<3 months)
* Major depressive symptoms as indicated by the Patient Health Questionnaire-2 depression screen score of 4 or more.
* Current or prior diagnosis of epilepsy, seizure disorder, dementia, migraines, balance disorder, or other neurological diseases that may prevent the use of virtual reality or adverse effects.
* Cardiopulmonary or pulmonary disorder with contraindication to physical exercise
* Pregnancy

Where this trial is running

Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainLow Back Painvirtual realityembodimentchronic painrehabilitation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.