Virtual reality rehabilitation for improving daily activities after stroke

Rehabilitation of Executive Functions in the Activities of the Daily Living of Chronic Post-stroke Patients: Using Virtual Reality and Computerized Rehabilitation to Simulate Real Environment for Rehabilitation.

Not applicable Interventional University Hospital, Toulouse · NCT04855903

This study tests if using virtual reality can help stroke survivors improve their daily activities by boosting their thinking skills.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment27 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Toulouse Academic / other
Locations3 sites (Bruges and 2 other locations)
Trial IDNCT04855903 on ClinicalTrials.gov

What this trial studies

This research evaluates the effects of a computerized cognitive rehabilitation program using virtual reality to enhance the ability of post-stroke patients to perform daily activities. The study focuses on individuals with dysexecutive disorders resulting from stroke, assessing their performance through a structured program that includes both pretreatment and treatment phases. Patients will engage in virtual reality sessions designed to improve executive functions, followed by a follow-up period to measure real-life application of skills learned. The approach utilizes a multiple baseline single case experimental design to track progress over time.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who have experienced a stroke at least six months prior and exhibit dysexecutive syndrome.

Not a fit: Patients with major visual or hearing deficits, other neurological pathologies, or those currently undergoing targeted rehabilitation for executive functions may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the ability of stroke survivors to perform daily activities, enhancing their independence and quality of life.

How similar studies have performed: While the use of virtual reality in rehabilitation is gaining traction, this specific approach targeting executive functions in post-stroke patients is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Vascular brain injury (stroke), in chronic phase (6 months or more after stroke), responsible for dysexecutive syndrome authenticated by the GREFEX/GRECO battery (Executive Function Evaluation Reflection Group)
* Men and women over the age of 18
* Presence of a caregiver
* Social Security affiliation
* Signing free and informed consent following clear and detailed information
* Sufficient understanding of the French language to participate in the study

Exclusion Criteria:

* Pregnant women (clinical examination)
* Alcohol and/or narcotics addiction
* Major hearing deficit
* Major visual deficit
* Neurological pathology other than stroke or psychiatric disorder
* Unstable epilepsy
* Patient undergoing rehabilitation at a liberal therapist targeting executive functions during study time
* Patient under safeguard of justice.
* Patient simultaneously participating in another research study

Where this trial is running

Bruges and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeN-of-1 trialscognitive rehabilitationcomputerized rehabilitationvirtual realityexecutive functionsoccupational therapypost-stroke rehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.