Virtual reality immersion versus midazolam to reduce anxiety before dacryocystorhinostomy
Official title: Randomized Clinical Trial for Comparison Between the Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery
Run by Cairo University · NCT07050095 · Data updated 2026-11-12
This project will test whether virtual reality immersion can reduce anxiety as well as midazolam in adults having dacryocystorhinostomy under general anesthesia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | December 30, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | July 3, 2025 |
| Trial ID | NCT07050095 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 years, ASA class I–II, of any sex, scheduled for dacryocystorhinostomy under general anesthesia are the ideal candidates.
✕Probably not a fit
Patients with cardiac or renal disease, seizure disorders, substance abuse, significant psychiatric or cognitive impairment, claustrophobia, severe eye problems, or those who cannot tolerate VR are unlikely to benefit or may be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing dacryocystorhinostomy under general anesthesia are assigned to either a virtual reality immersion session before surgery or to standard midazolam premedication. The study measures preoperative anxiety levels, intraoperative hemodynamic stability, and records sedation-related adverse events. Virtual reality offers an immersive non-pharmacologic experience, while midazolam acts on GABAA receptors to produce sedation. Outcomes will compare anxiolytic effect and safety to determine if VR can be a viable alternative to drug premedication.
Why it matters
Potential benefit: If successful, VR could provide a non-drug way to lower preoperative anxiety and reduce sedative-related side effects.
How similar studies have gone: Previous small trials and reviews have shown that virtual reality can reduce perioperative anxiety and pain in various surgical settings, though direct comparisons with midazolam are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-65. * Both sexes. * American Society of Anesthesiologists (ASA) classification: I - II. * Patient undergoing Dacryocystorhinostomy Surgery (DCR) operation under general anesthesia. Exclusion Criteria: * Patient refusal. * Patients with cardiac diseases. * Patients with renal diseases. * Patients with drug sensitivity and seizures. * Substance abuse and addiction. * Claustrophobia. * Patients with cerebrovascular disease. * Psychiatric and cognitive disorder. * Patients with severe teary eyes and blurring of vision. * Patients who express discomfort during the test.
Where it's running
-
Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Hebatullah S Abdelhamid, MD
- Email: drhebasalah593@gmail.com
- Phone: 002 01044512277
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.