Virtual reality headsets to reduce anxiety before surgery

Effect of Virtual Reality Use on Preoperative Anxiety: A Prospective, Randomized, Controlled Interventional Study (VeRA-Study)

Not applicable Interventional University of Bonn · NCT07270445

We will try using a virtual reality headset before elective surgery to see if it lowers anxiety in adult patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment172 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Bonn Academic / other
Locations1 site (Bonn)
Trial IDNCT07270445 on ClinicalTrials.gov

What this trial studies

This is a prospective, randomized, controlled study at University Hospital Bonn comparing preoperative virtual reality headset use to usual care in adults having elective surgery. After informed consent, participants are randomized and stratified by whether relatives are present during the preoperative process. Anxiety is measured with the STOA and APAIS questionnaires, stress and pain with an NRS, simulator sickness with the SSQ, and brain activity is monitored using a BIS EEG device. Key exclusions include epilepsy, certain psychiatric diagnoses, pacemakers/defibrillators, need for sedative premedication, and inability to communicate in German.

Who should consider this trial

Good fit: Adults aged 18 or older scheduled for elective surgery who can read and speak German, have no visual or hearing impairments, and are not receiving sedative premedication are the ideal candidates.

Not a fit: Patients having emergency surgery, with epilepsy or certain psychiatric disorders, with pacemakers/defibrillators, expected ICU/IMC admission, or with communication/visual limitations are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If effective, using a VR headset could lower preoperative anxiety, reduce perioperative stress and pain, and possibly decrease reliance on sedative medications.

How similar studies have performed: Previous smaller randomized trials and reviews in procedural and perioperative settings have shown that VR can reduce anxiety and pain in some patients, but results are variable and larger confirmatory trials are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Written informed consent
* All consecutive patients undergoing elective, outpatient, or inpatient surgery
* No communication difficulties (e.g., hearing impairment) and good command of the German language
* No visual impairment
* Planned extubation immediately after surgery

Exclusion Criteria:

* Patients undergoing emergency surgery
* Patients with documented psychiatric disorders (e.g., bipolar disorder), confusion, or epilepsy
* Individuals admitted due to a court or official order
* Expected non-compliance with the study protocol
* Expected admission to an intermediate care unit (IMC) or intensive care unit (ICU)
* Patients receiving sedative or anxiolytic medication for premedication
* Patients with pacemakers or defibrillators

Where this trial is running

Bonn

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnxietyVR glassesanxiety
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.