Virtual reality eye exercises for ocular cranial nerve palsies
Head-Cancelled Virtual Reality for Rehabilitation of Ocular Cranial Nerve Palsies
NA · Brooks Rehabilitation · NCT06417216
This study is testing if virtual reality eye exercises can help people with certain eye movement problems improve their eye motion compared to regular exercises.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Brooks Rehabilitation (other) |
| Locations | 2 sites (Jacksonville, Florida and 1 other locations) |
| Trial ID | NCT06417216 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of eye exercises performed in virtual reality for patients with abducens palsy and internuclear ophthalmoplegia. Participants will engage in tasks under two conditions: head-cancelled, where head movement does not shift gaze, and head-active, where normal head movement is allowed. The hypothesis is that the head-cancelled condition will encourage greater eye movement, potentially improving ocular range of motion. The study will compare eye movement amplitude between these conditions and include a control group with normal vision for additional analysis.
Who should consider this trial
Good fit: Ideal candidates are individuals with unilateral ocular cranial nerve palsy and at least a 50% limitation in eye movement.
Not a fit: Patients with bilateral ocular cranial nerve palsies or those with better than 50% range of motion will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance eye movement and improve quality of life for patients with ocular cranial nerve palsies.
How similar studies have performed: While the use of virtual reality for rehabilitation is gaining traction, this specific approach to ocular cranial nerve palsies is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
OCNP Group Inclusion Criteria: * Presence of OCNP in one eye with 50% range-of-motion limitation or worse * Able to provide informed consent and will be able to fluently read and understand spoken English OCNP Group Exclusion Criteria: * Presence of bilateral OCNP * Range of motion better than 50% * Visual acuity worse than 20/100 in either eye * Greater than 4-line difference in visual acuity between the eyes, * Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset Participants will be excluded if they are unable to participate if inclusion criteria are not met. Normal Group Inclusion Criteria: * Absence of OCNP or other neurological or neuro-ophthalmic diseases * No strabismus * Have normal or near-normal vision with glasses or contact lenses. * Be able to provide informed consent and will be able to fluently read and understand spoken English Normal Group Exclusion Criteria: * Visual acuity worse than 20/100 in either eye * Greater than 4-line difference in visual acuity between the eyes * Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset * Known inability to tolerate visual testing of at least 20 minutes continuously.
Where this trial is running
Jacksonville, Florida and 1 other locations
- Brooks Rehabilitation Hospital — Jacksonville, Florida, United States (RECRUITING)
- Vision Source of Worcester — Worcester, Massachusetts, United States (RECRUITING)
Study contacts
- Study coordinator: Kevin Houston, OD
- Email: khouston@wsvisionsource.com
- Phone: 508-753-5103
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Internuclear Ophthalmoplegia, Palsy, Abducens