Virtual Reality Exposure Therapy for Gambling Disorder
Official title: Virtual Reality Exposure Therapy for Gambling Disorder: Randomized Controlled Trial
Run by University Hospital, Lille · NCT04467502 · Data updated 2026-11-12
This study tests whether virtual reality exposure therapy added to CBT can reduce gambling disorder symptoms as well as traditional imaginal exposure therapy in adults seeking treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 124 (estimated) |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 10 sites (Amiens and 9 other locations) |
| Status | Recruiting |
| Started | July 12, 2023 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT04467502 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults seeking GD treatment who meet DSM-5 criteria, have SOGS ≥ 5, gamble at least monthly at casinos, understand French, and can consent.
✕Probably not a fit
Individuals not responding to exposure-based approaches or with contraindications to VR may see limited benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In adults diagnosed with gambling disorder, the study compares virtual reality exposure therapy (VRET) embedded in cognitive-behavioral therapy to imaginal exposure therapy within CBT. The trial examines non-inferiority on gambling disorder symptoms after 12 treatment sessions and again over 12 months of follow-up. Secondary measures include gambling behavior, craving, gambling-related cognitions, and changes in anxiety and depressive symptoms. Interventions consist of CBT for GD, imaginal cue exposure, and VRET in a controlled outpatient setting across multiple French centers. Eligibility requires DSM-5 GD, a SOGS score of 5 or higher, regular casino gambling, French comprehension, and consent to participate.
Why it matters
Potential benefit: If successful, patients could have an effective, possibly more convenient exposure-based treatment option using VR that fits into standard care.
How similar studies have gone: Previous exposure-based therapies have shown benefits in GD, but the VR approach for GD is a newer, comparative strategy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Seek treatment for GD within one of health care facilities participating in the research (first request for treatment and not patients already receiving treatment for gambling disorder in the care center). * Meet a current diagnosis of gambling disorder according to DSM-5 criteria and with a South Oaks Gambling Screen (SOGS) score ≥ 5 * Meet a casino gambling behavior with a casino gambling frequency ≥ 1 time every two months during the last 12 months * Have a sufficient understanding of French for therapy * Beneficiary of the French social security system * Give an informed consent to participate * Willing to comply with all study procedures and duration Exclusion Criteria: * Visual disturbance making impossible the use of virtual reality equipment (e.g. advanced retinal degeneration, central scotoma, age-related macular degeneration) * Pregnant woman * Minor or adult under guardianship, conservatorship, under judicial protection, persons deprived of their liberty * Balance disorder (e.g. cerebellar disorder, inner ear disorder) * Photosensitive epilepsy * Refusal to participate
Where it's running
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CH Seclin Carvin CSAPA
Seclin, France Recruiting -
CHU Amiens-Picardie
Amiens, France Not yet recruiting -
CH Boulogne sur mer CSAPA
Boulogne-sur-Mer, France Not yet recruiting -
CHU de Caen
Caen, France Not yet recruiting -
Hôpital Fontan, CHU lille
Lille, France Not yet recruiting -
Assoriation Cédragir Lomme CSAPA
Lomme, France Not yet recruiting
Show 4 more locations
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CH de l'arrondissement de Montreuil / CSAPA
Montreuil-sur-Mer, France Not yet recruiting -
CHU Rouen
Rouen, France Not yet recruiting -
CH de Saint Amand les Eaux
Saint-Amand-les-Eaux, France Not yet recruiting -
Association GREID ValenciennesCSAPA
Valenciennes, France Not yet recruiting
Study contacts
- Principal investigator: Pierre TAQUET, PhD — University Hospital, Lille
- Study coordinator: Pierre TAQUET, PhD
- Email: pierre.taquet@chru-lille.fr
- Phone: 0320445838
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.