Virtual reality exercises to improve attention in brain injury patients
Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury
This study is testing if a virtual reality exercise program can help people with brain injuries pay better attention compared to regular therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 135 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mindmaze SA Industry-sponsored |
| Locations | 1 site (Lausanne) |
| Trial ID | NCT05728840 on ClinicalTrials.gov |
What this trial studies
This study evaluates the efficacy of a virtual reality (VR) training program designed to enhance attention and executive functions in patients with acquired brain injuries, including stroke. It involves a three-arm, double-blind, randomized, actively controlled design with 45 participants in each group. The VR program consists of gamified cognitive activities tailored to the patient's level of impairment, assessed through short evaluations. The primary goal is to determine if daily VR-based training can significantly improve attentional abilities compared to standard neuropsychological care.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have experienced a stroke within the last month and have documented attention deficits.
Not a fit: Patients with major psychiatric co-morbidities, severe cognitive deficits, or those unable to participate in VR activities may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel and effective method for improving attention deficits in patients recovering from brain injuries.
How similar studies have performed: While the use of VR in cognitive rehabilitation is emerging, this specific approach targeting attention deficits in stroke patients is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Time from stroke onset \< 1 month * Objective pathological performance on at least one standardized test or subtest on attention during standard neuropsychological evaluation * Brain injury documented by routine neuroradiological examination (computed tomography or magnetic resonance imaging scan) * Able to give informed consent as documented by signature * Age \>= 18 years old Exclusion Criteria: * Epilepsy * Inability or contraindications to undergo the investigated intervention * Major psychiatric co-morbidity * Major neurocognitive deficits (e.g. dementia) * Incapacity to discriminate colors * General cognitive state preventing to understand and perform the tasks * Decision to not be informed of incidental findings
Where this trial is running
Lausanne
- University of Lausanne Hospitals — Lausanne, Switzerland (Recruiting)
Study contacts
- Principal investigator: Sonia Crottaz-Herbette — University of Lausanne Hospitals
- Study coordinator: Sonia Crottaz-Herbette
- Email: sonia.crottaz-herbette@chuv.ch
- Phone: +41213149348
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.