Virtual reality-assisted dual-task training to boost muscle oxygenation in COPD
Official title: Investigation of the Effects of Virtual Reality-Assisted Dual Task Training on Cerebral, Peripheral, and Respiratory Muscle Oxygenation in Patients With Chronic Obstructive Pulmonary Disease
Run by Istinye University · NCT07015216 · Data updated 2026-11-12
We will test whether virtual reality-assisted exercises that combine thinking and moving can improve muscle oxygen levels in people with moderate COPD (GOLD stage 2-3).
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Istinye University Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | July 12, 2025 |
| Main results expected | September 15, 2025 |
| Study ends | January 10, 2026 |
| Registry record updated | June 22, 2025 |
| Trial ID | NCT07015216 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are ambulatory adults with COPD GOLD stage 2 or 3 who have adequate cognition (MMSE ≥ 23), no major visual, vestibular, orthopedic, or cardiovascular contraindications, and are not in an acute exacerbation.
✕Probably not a fit
People with very severe COPD (e.g., GOLD stage 4), significant cognitive impairment, active cardiovascular disease, vestibular or visual problems, ongoing acute exacerbation, or other conditions that prevent exercise are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an interventional comparison of a virtual reality-assisted dual-task training program versus a conventional therapy program in ambulatory patients with COPD GOLD stage 2 or 3. Participants who meet cognitive and safety criteria (MMSE ≥ 23, no major cardiovascular, vestibular, visual, or orthopedic contraindications) will undergo supervised training and physiological monitoring. The main focus is on muscle oxygenation and related exercise and cognitive-motor measures, with prefrontal cortex activity and exercise tolerance considered in the rationale. The study is conducted in person at Istinye University in Istanbul.
Why it matters
Potential benefit: If successful, it could improve muscle oxygenation, exercise tolerance, and daily functioning for people with moderate COPD.
How similar studies have gone: Some preliminary and pilot work shows dual-task and VR-based rehabilitation can help gait, balance, and cognitive-motor function, but evidence specifically in COPD is limited and mixed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of COPD stage 2 or 3 according to GOLD classification * No orthopedic and/or neuromuscular conditions that would interfere with dual-task training * Ability to ambulate * Adequate cognitive level to participate in the training (Mini Mental State Examination score ≥ 23) * Voluntary participation Exclusion Criteria: * Presence of vestibular problems that would interfere with virtual reality applications * Visual impairments * Any medical condition contraindicating exercise participation * Being in an acute exacerbation period * Having an active infection * Diagnosis of cancer * Known cardiovascular disease
Where it's running
-
Istınye University, Istanbul,
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Berrak VARHAN Professor, Dr, PT
- Email: berrak.varhan@istinye.edu.tr
- Phone: 0850 283 6000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.