Virtual meaning-centered group therapy for adults with a history of cancer
Official title: Evaluation of Meaning-centered Group Psychotherapy in Integrative Medicine
Run by M.D. Anderson Cancer Center · NCT07147205 · Data updated 2026-11-12
This program will test whether a virtual meaning-centered group therapy helps adults with a history of cancer reduce anxiety and depression and improve quality of life and sense of meaning.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 72 (estimated) |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | October 3, 2025 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2029 |
| Registry record updated | September 16, 2026 |
| Trial ID | NCT07147205 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with a diagnosis or history of malignant cancer who read and speak English, have access to a device for Zoom, and have been referred to and evaluated by the MD Anderson Integrative Medicine Clinic are ideal candidates.
✕Probably not a fit
Children, pregnant women, cognitively impaired individuals, people who cannot use Zoom or do not speak English, or those who do not attend sessions are unlikely to benefit from this virtual group program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with a diagnosis or history of malignant cancer who are referred to the MD Anderson Integrative Medicine Clinic join closed, 90-minute virtual meaning-centered group psychotherapy sessions delivered via Zoom. Participants complete baseline and post-participation questionnaires measuring anxiety, depression, quality of life, meaning in life, and fear of cancer recurrence, and provide satisfaction and qualitative feedback about the virtual group experience and therapy adaptations. The protocol includes descriptive analyses of participant demographics, clinical characteristics, IMC utilization, and session attendance, plus pre/post comparisons of symptom and outcome measures. Secondary analyses examine whether baseline characteristics predict number of sessions attended and whether attendance is associated with changes in outcomes.
Why it matters
Potential benefit: If successful, participants could experience greater sense of meaning, reduced anxiety and depression, and improved overall quality of life.
How similar studies have gone: Previous research on meaning-centered psychotherapy for cancer patients has demonstrated improvements in sense of meaning and psychological symptoms in comparable populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Eligibility Criteria 1. Age 18 or older. 2. Male or female. 3. Diagnosis or history of malignant cancer (excluding non-melanoma skin cancer) or tumor disease. 4. Able to read, write, and speak in English. 5. Has access to iOS or Android smartphone, computer, or tablet or device capable of logging onto Zoom. 6. Referred to the Integrative Medicine Clinic, completed consult with IMC physician, referred to health psychology and completed health psychology assessment. 7. Participates in at least one MCGP group session. 8. Willing to review informed consent statement and agree to complete questionnaires. Exclusion Criteria 1. Children will not be enrolled in this study. 2. Pregnant women will not be enrolled in this study. 3. Cognitively impaired subjects will not be enrolled in this study.
Where it's running
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MD Anderson Cancer Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Elizabeth C Conti, MD — M.D. Anderson Cancer Center
- Study coordinator: Elizabeth C Conti, MD
- Email: ecconti@mdanderson.org
- Phone: 7135637630
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.