Virtual exercise program for lung cancer patients

Virtual Personalized Exercise Program for Subjects With Lung Cancer: a Feasibility Study

This study is testing a personalized virtual exercise program for lung cancer patients to see if it helps them feel better and improve their health over a year.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 60 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Northwell Health (other)
• Drugs / interventions: chemotherapy, radiation
• Locations: 1 site (New Hyde Park, New York)
• Trial ID: NCT06540495 on ClinicalTrials.gov

What this trial studies

This study provides a customized virtual exercise program for lung cancer patients at R.J. Zuckerberg Cancer Center, aiming to improve their functional status and overall outcomes. Participants will be evaluated by physical therapy and rehabilitation medicine doctors before enrolling in the program, which is accessible via personal devices. The program includes pulmonary function tests, Six Minute Walk Tests, and quality of life assessments at various intervals over a 12-month period to measure feasibility and usability.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with non-small cell lung cancer who can engage in a virtual exercise platform.

Not a fit: Patients who are unable to participate in virtual exercise or have an ECOG performance status greater than 2 may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could enhance the physical well-being and quality of life for lung cancer patients.

How similar studies have performed: Other studies have shown positive outcomes with exercise interventions for cancer patients, indicating this approach is promising.

Eligibility criteria

Inclusion Criteria:

(1) Adults aged 18 and older (2) Have an ECOG PS of 0-2 (3) Have the ability to provide informed consent (4) Have the ability to engage in a virtual exercise platform (5) Commit to all study procedures as per protocol (6) Are deemed appropriate for virtual exercise program by the PM\&R team (7) English speaking (8) Subjects with non-small cell lung cancer who belong to any of the three cohorts: (i) Cohort A: Peri-operative (subjects starting neoadjuvant chemotherapy or within 4-8 weeks after curative-intent thoracic surgery which could be segmentectomy, lobectomy of pneumonectomy), irrespective of adjuvant treatment - expected recruitment: 15 subjects (ii) Cohort B: Subjects starting definitive chemotherapy and radiation for locally advanced cancer - expected recruitment: 15 subjects (iii) Cohort C: Subjects with stage IV metastatic non-small cell lung cancer irrespective of type of treatment- expected recruitment: 30 subjects

Exclusion Criteria:

1. Unable to render informed consent
2. No other current active malignancy (beside lung cancer) at time of enrollment
3. Any contraindication to participating physically in an exercise program
4. Pregnant or breastfeeding at the time of screening visit
5. Any of the following contraindications to exercise use: acute post-operative subjects (within 8 weeks of operation; subjects with extreme fatigue, anemia, or ataxia; and general cardiovascular and respiratory contraindications for an exercise regimen.
6. Lack of proficiency in English sufficient for comprehension of trial source documents including the protocol, consent, and questionnaires.

Where this trial is running

New Hyde Park, New York

• Northwell Health — New Hyde Park, New York, United States (RECRUITING)

Study contacts

• Study coordinator: Tracy Green

Conditions: Lung Cancer, Exercise