Video game breathing exercises for breathing problems in Asthma-COPD Overlap Syndrome
Investigation of the Effect of Video Game-Based Breathing Exercises on Dysfunctional Respiration in Patients With Asthma-COPD Overlap Syndrome (ACOS)
This trial will test whether video game-based breathing exercises help people aged 40–80 with Asthma-COPD Overlap Syndrome who have dysfunctional breathing patterns.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Istinye University Academic / other |
| Locations | 1 site (Kocaeli, Izmit) |
| Trial ID | NCT07185178 on ClinicalTrials.gov |
What this trial studies
Adults with Asthma-COPD Overlap Syndrome (ACOS) and evidence of dysfunctional breathing are enrolled and compared between a program of video game–guided breathing exercises and a control group. Participants must be clinically stable and able to use video game interfaces, and those with major comorbidities or contraindications to pulmonary rehabilitation are excluded. Outcomes focus on dysfunctional breathing measures (e.g., Nijmegen Questionnaire) and related functional and quality-of-life metrics. The intervention is delivered in a clinical setting at the enrolling hospital and aims to improve adherence and breathing technique through gamified feedback.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40–80 with a diagnosis of ACOS, a Nijmegen Questionnaire score ≥23, clinically stable status, no severe asthma or COPD, and the cognitive ability to use video game interfaces.
Not a fit: Patients with severe asthma or COPD, recent exacerbations, contraindications to pulmonary rehabilitation, active cancer, severe cardiovascular disease, cognitive or visual impairment, or epilepsy/vertigo are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the approach could reduce dysfunctional breathing and improve symptoms, exercise capacity, and quality of life for people with ACOS.
How similar studies have performed: Small studies of gamified or virtual-reality rehabilitation in COPD or asthma show improved engagement and some clinical gains, but direct evidence specifically in ACOS is very limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 40 and 80 years * Diagnosed with Asthma-COPD Overlap Syndrome (ACOS) * Nijmegen Questionnaire score ≥ 23 * No severe asthma * No severe COPD * In a stable condition (no acute exacerbation in the last 4 weeks) * To have the cognitive level suitable to adapt to video games Exclusion Criteria: * Contraindicated for pulmonary rehabilitation * Diagnosed with cancer * Having severe cardiovascular disease * History of thoracic surgery * Presence of acute infectious disease * Cognitive impairment * Presence of vertigo, epilepsy, or visual impairment
Where this trial is running
Kocaeli, Izmit
- Kocaeli University Training and Research Hospital — Kocaeli, Izmit, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: HÜSNA GÜZEL, PT,PhD (c) — Istinye University
- Study coordinator: HÜSNA GÜZEL, PT,PhD (c)
- Email: h.guzel.ftr@gmail.com
- Phone: +905071194128
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.