Vibration to improve head posture in cervical dystonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares different intensities of cervical vibrotactile stimulation to see how each affects abnormal head posture in adults with cervical dystonia. Participants receive controlled vibration to neck muscles while researchers measure changes in head alignment and posture. The study also measures proprioception at the neck, wrist, and ankle and compares those results with age- and sex-matched healthy controls to quantify impairment and any short-term improvement from neck vibration. Recruitment excludes people with other neurological or peripheral nerve diseases, implanted deep brain stimulators or prior denervation surgery, severe tremor, or regular use of benzodiazepines or antidepressants, and all testing is done in-person at the Human Sensorimotor Control Laboratory in Minneapolis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Confirmed diagnosis of adult-onset, isolated idiopathic cervical dystonia.

Exclusion Criteria:

History of other neurological diseases, including Parkinson's disease, essential tremor, dementia, etc.

History of peripheral nervous system disease that can impair proprioception. Deep brain stimulation implanted or denervation surgery. UBACC score lower than 15. Severe head tremors or facial muscle contractions. Regular intake of benzodiazepines or antidepressant medication.

Where it's running

• Human Sensorimotor Control Laboratory
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Jürgen Konczak, PhD — University of Minnesota
• Study coordinator: Jürgen Konczak, PhD
• Email: jkonczak@umn.edu
• Phone: 612-624-4370

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Targeted Focused Ultrasound for Cervical Dystonia

  This trial tests whether applying theta burst focused ultrasound to brain regions GPi or DN, or a sham, can help people with cervical dystonia.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT07690514

• Noninvasive brain stimulation for cervical dystonia using continuous theta-burst in a sham-controlled trial

  This study tests whether delivering continuous theta-burst stimulation to the brain can reduce neck dystonia symptoms compared with sham stimulation.

  Recruiting Fondazione Policlinico Universitario Campus Bio-Medico · Roma, Roma · NCT07681284

• Adding zinc to Botox for cervical dystonia

  This will test whether taking daily zinc citrate after a Botox injection helps people with cervical dystonia keep symptom relief longer.

  Recruiting Phase 2 University of Florida · Gainesville, Florida · NCT07140874

• IPN10200 treatment for cervical dystonia in adults

  This trial will test whether a single injection of IPN10200 (one of two doses) reduces neck posture problems, pain, and disability better than placebo in adults with cervical dystonia.

  Recruiting at 27 sites Phase 2 Ipsen · Tucson, Arizona and 44 other locations · NCT06937931

• Using Valbenazine with Botulinum Toxin for Cervical Dystonia

  This study is testing if adding a medication called valbenazine to botulinum toxin injections can help people with cervical dystonia feel better and improve their quality of life.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT06771323

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.