Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Vibration of hamstring tendons to change knee sensation and movement

Official title: Stimolazione Vibratoria Non-invasiva Per il Miglioramento Del Ritorno Sensoriale e Della Performance Motoria in Atleti Con Lesione al Legamento Crociato Anteriore

Run by University of Milano Bicocca · NCT07424066 · Data updated 2026-11-12

This test tries gentle vibration on the back of the thigh to see if it changes knee muscle activity and movement in healthy adults.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment35 (estimated)
SponsorUniversity of Milano Bicocca
Academic / other
Locations1 site (Milan, Milan)
StatusRecruiting
StartedMay 20, 2025
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 20, 2026
Trial IDNCT07424066 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults aged 18 years or older without neurological disorders, significant musculoskeletal injuries, or cardiorespiratory disease are ideal candidates.

Probably not a fit

People with neurological disorders, prior musculoskeletal injuries that affect movement, or cardiorespiratory conditions are excluded and unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an interventional cross-sectional experiment in healthy adults that applies non-invasive vibration to the hamstring (tendon) and compares knee flexion and extension movements with and without vibration. Participants will perform isometric and concentric knee contractions while investigators record muscle activity and knee angular trajectories and velocities. The team hypothesizes that vibration will increase hamstring (flexor) activity and decrease quadriceps (extensor) activity, producing measurable changes in movement trajectories and speed. Results will be compared across conditions to quantify the immediate effect of tendon vibration on somatosensory input and motor performance.

Why it matters

Potential benefit: If successful, this could point to a simple non-invasive way to modify proprioceptive input and influence knee motor control that may inform rehabilitation approaches.

How similar studies have gone: Previous laboratory studies using tendon vibration have reliably altered muscle activation patterns and proprioceptive perception, so this approach builds on established experimental findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age equal to or greater than 18 years.

Exclusion Criteria:

* Neurological disorders.
* Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements.
* Cardiorespiratory disorders.

Where it's running

  • Istituto Auxologico Italiano, Clinica Capitanio
    Milan, Milan, Italy
    Recruiting

Study contacts

  • Principal investigator: Cristiano Alessandro, Engineering — University of Milano Bicocca
  • Study coordinator: Stefano Scarano, Medical Doctor
  • Email: s.scarano@auxologico.it
  • Phone: +3902619116717

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.