Vibration of hamstring tendons to change knee sensation and movement

Stimolazione Vibratoria Non-invasiva Per il Miglioramento Del Ritorno Sensoriale e Della Performance Motoria in Atleti Con Lesione al Legamento Crociato Anteriore

NA · University of Milano Bicocca · NCT07424066

This test tries gentle vibration on the back of the thigh to see if it changes knee muscle activity and movement in healthy adults.

Quick facts

PhaseNA
Study typeInterventional
Enrollment35 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Milano Bicocca (other)
Locations1 site (Milan, Milan)
Trial IDNCT07424066 on ClinicalTrials.gov

What this trial studies

This is an interventional cross-sectional experiment in healthy adults that applies non-invasive vibration to the hamstring (tendon) and compares knee flexion and extension movements with and without vibration. Participants will perform isometric and concentric knee contractions while investigators record muscle activity and knee angular trajectories and velocities. The team hypothesizes that vibration will increase hamstring (flexor) activity and decrease quadriceps (extensor) activity, producing measurable changes in movement trajectories and speed. Results will be compared across conditions to quantify the immediate effect of tendon vibration on somatosensory input and motor performance.

Who should consider this trial

Good fit: Healthy adults aged 18 years or older without neurological disorders, significant musculoskeletal injuries, or cardiorespiratory disease are ideal candidates.

Not a fit: People with neurological disorders, prior musculoskeletal injuries that affect movement, or cardiorespiratory conditions are excluded and unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, this could point to a simple non-invasive way to modify proprioceptive input and influence knee motor control that may inform rehabilitation approaches.

How similar studies have performed: Previous laboratory studies using tendon vibration have reliably altered muscle activation patterns and proprioceptive perception, so this approach builds on established experimental findings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age equal to or greater than 18 years.

Exclusion Criteria:

* Neurological disorders.
* Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements.
* Cardiorespiratory disorders.

Where this trial is running

Milan, Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vibration, vibratory stimulation, muscle spindle, muscle contraction, spinal reflex, somatosensory system

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.