Clinical trial Recruiting at 1 site Observational Ages 18 to 50

Vaspin gene changes and blood vaspin levels in people with psoriasis

Official title: Correlation Between Vaspin Gene Polymorphism and Serum Vaspin Levels in Psoriasis Vulgaris and Its Relation to Pathogenesis and Risk of the Disease

Run by Aswan University · NCT07320872 · Data updated 2026-11-12

This test will see if specific vaspin gene variants are linked to blood vaspin levels in people with psoriasis.

More Psoriasis Vulgaris trials

Quick facts

Study typeObservational
Ages18 Years to 50 Years
SexAll
Enrollment60 (estimated)
SponsorAswan University
Academic / other
Drugs / interventionsmethotrexate
Locations1 site (Aswān)
StatusRecruiting
StartedAugust 10, 2025
Main results expectedAugust 10, 2026
Study endsAugust 20, 2026
Registry record updatedJanuary 6, 2026
Trial IDNCT07320872 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People of any age and gender with newly diagnosed psoriasis or who have been off psoriasis treatment for at least six months, who are not pregnant or breastfeeding and do not have chronic systemic or other inflammatory diseases, are ideal candidates.

Probably not a fit

Patients who are pregnant or lactating, have chronic cardiac, hepatic, or renal disease, malignancy, other inflammatory or autoimmune disorders, or who are currently on psoriasis treatment are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, cross-sectional study at Aswan University Hospital will enroll patients with psoriasis to measure serum vaspin levels and to genotype vaspin gene polymorphisms (SERPNA12). Blood samples will be taken for serum protein measurement and DNA analysis, and clinical information including treatment history will be recorded. Eligible participants are newly diagnosed patients or those off treatment for at least six months, while individuals with pregnancy, lactation, chronic systemic disease, malignancy, or other inflammatory conditions are excluded. Data analysis will look for correlations between genotype variants, serum vaspin concentrations, and clinical features of psoriasis.

Why it matters

Potential benefit: If a link is found, it could help identify genetic markers tied to disease features or metabolic risks and guide future personalized research or risk stratification.

How similar studies have gone: Prior studies have linked adipokines to psoriasis and cardiometabolic risk, but research specifically on vaspin gene polymorphisms is limited and has yielded mixed or preliminary results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Newly diagnosed cases or stopped treatment of at least 6 months of psoriasis patients.
* Pateints with any age and gender.

Exclusion Criteria:

* Pregnancy and lactation.
* Patients with chronic diseases: cardiac diseases, hepatic disorders, chronic renal failure or malignancies.
* Patients with associated inflammatory disease such as infections and autoimmune diseases.

Where it's running

  • Aswan University Hospital
    Aswān, Egypt
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.