Validation of the Cukurova Score for ovarian cancer treatment decisions
Official title: Cukurova Score Validation Study in Prediction of Primary Cytoreduction in Advanced Ovarian Cancer
Run by Cukurova University · NCT06378905 · Data updated 2026-11-12
This study is testing a new scoring system to help doctors decide the best treatment options for patients with advanced ovarian cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | Women only |
| Enrollment | 130 (estimated) |
| Sponsor | Cukurova University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Adana) |
| Status | Recruiting |
| Started | May 30, 2024 |
| Main results expected | March 2026 |
| Study ends | March 2027 |
| Registry record updated | August 29, 2024 |
| Trial ID | NCT06378905 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and over with pathologically confirmed Stage III-IV epithelial ovarian cancer.
✕Probably not a fit
Patients with early-stage (Stage I-II) or non-epithelial ovarian cancers will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to validate the Cukurova score, which prioritizes surgical procedures for patients with advanced-stage epithelial ovarian cancer based on radiological imaging and clinical performance rather than solely on tumor burden. The study will include patients who are suspected to have advanced ovarian cancer and have been pathologically confirmed to have Stage III-IV disease. By assessing the effectiveness of the Cukurova score, the study seeks to improve decision-making regarding primary cytoreductive surgery and neoadjuvant chemotherapy. The ultimate goal is to enhance surgical outcomes and patient management in advanced ovarian cancer cases.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and tailored treatment strategies for patients with advanced epithelial ovarian cancer.
How similar studies have gone: While there have been various scoring systems developed for surgical decision-making in ovarian cancer, the Cukurova score represents a novel approach that has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years old and over * Suspected advanced ovarian/fallopian tube/ primary peritoneal carcinomatosis on imaging * Pathologically confirmed Stage III-IV epithelial ovarian cancer/fallopian tube/ primary peritoneal carcinomatosis * Consent to participate in the study Exclusion Criteria: * Stage I-II epithelial ovarian/fallopian tube/peritoneal cancer * Nonepithelial Ovarian Cancer * Benign Ovarian tumors * Borderline Ovarian Tumors * Metastatic Ovarian Tumors * Rejecting to Participate in the Study * \<18 years old
Where it's running
-
Cukurova University
Adana, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Ghanim Khatib, MD
- Email: ghanim.khatib@gmail.com
- Phone: +903223386060
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
VT-101 in Advanced Ovarian Cancer: early safety study in adults
This early-phase trial tests VT-101 in adult women with advanced, recurrent, or relapsed epithelial ovarian cancer to see if it is safe, how the body handles it, and whether there are any initial signs of activity.
-
Torvutatug samrotecan plus bevacizumab as first-line maintenance in non-HRD advanced epithelial ovarian cancer
This trial tests whether adding torvu-samrotecan to bevacizumab after standard chemotherapy helps people with non-HRD advanced epithelial ovarian cancer live longer without the cancer worsening compared with bevacizumab alone.
-
Whole-body metabolic activity as a predictor of chemotherapy response in epithelial ovarian cancer
This study tests whether whole-body metabolic activity can predict how well epithelial ovarian cancer responds to chemotherapy.
-
[68Ga]BED003 PET imaging to see fibroblast activity in selected cancers
This study tests a PET imaging agent, [68Ga]BED003, to see how well it detects tumors in colorectal, gastric, pancreatic, ovarian, and invasive lobular breast cancers.
-
Dual-target CAR-NK Cells for Peritoneal Cancers of the Ovary, Fallopian Tube, or Pseudoperitoneal Disease
This trial tests a dual-target CAR-NK cell therapy for people with recurrent or hard-to-treat epithelial ovarian, fallopian tube, or primary peritoneal cancer who express two or more specific tumor markers.
-
Dual-Target CAR-NK Cells for Recurrent or Refractory Epithelial Ovarian Cancer
This trial tests EB-DUALNK, a dual-target CAR-NK cell therapy, in adults with recurrent or refractory epithelial ovarian, fallopian tube, or peritoneal cancer to see if it can safely help the cancer shrink or stay controlled.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.