Validation of saliva tests for COVID-19 detection and monitoring
COVID-19 in Baselland: Validation of Simple and Accurate Tests for COVID-19 Detection, Monitoring and Tracing (ACCURATE-BL-COVID-19)
This study is testing different saliva tests for COVID-19 to see if they can accurately help identify the virus in people who have symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Basel, Switzerland Academic / other |
| Locations | 1 site (Liestal) |
| Trial ID | NCT04625257 on ClinicalTrials.gov |
What this trial studies
This study aims to establish a reliable and scalable platform for COVID-19 viral nucleic acid analysis using saliva samples. It focuses on validating various diagnostic methods, including next-generation sequencing (NGS), loop-mediated amplification (LAMP) assays, and point-of-care tests (POCT) for rapid detection of viral antigens. The goal is to enhance contact tracing efforts in the canton of Baselland, Switzerland, by providing accurate testing solutions. The study will involve symptomatic patients undergoing COVID-19 testing.
Who should consider this trial
Good fit: Ideal candidates for this study are symptomatic individuals who are being tested for COVID-19.
Not a fit: Patients who are mentally incompetent adults will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more accessible and efficient method for COVID-19 detection and monitoring, improving public health responses.
How similar studies have performed: Other studies have shown success with saliva-based testing approaches for COVID-19, indicating potential for this method.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic patients getting tested for COVID-19 Exclusion Criteria: * mentally incompetent adults
Where this trial is running
Liestal
- Cantonal Office of Public Health, Economics and Health Directorate, Canton Basel-Landschaft — Liestal, Switzerland (Recruiting)
Study contacts
- Principal investigator: Miodrag Savic, Dr. med. Dr. med. dent. — Cantonal Office of Public Health, Economics and Health Directorate, Canton Basel-Landschaft
- Study coordinator: Miodrag Savic, Dr. med. Dr. med. dent.
- Email: miodrag.savic@usb.ch
- Phone: +41 79 485 31 13
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.