Validation of drug measurement methods in different body fluids
Official title: Validation of Drug Assays in Various Biological Matrices
Run by University of Liverpool · NCT02283112 · Data updated 2026-11-12
This study is testing how well a new method can measure drug levels in different body fluids to help ensure accurate results for people taking various medications.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University of Liverpool Academic / other |
| Locations | 1 site (Liverpool) |
| Status | Recruiting |
| Started | October 2014 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT02283112 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals over 18 years of age who are either receiving or not receiving specific medications.
✕Probably not a fit
Patients who are unable to give informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on validating the accuracy and precision of drug assays that measure drug concentrations in various biological matrices using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). It involves collecting samples from different bodily fluids to quantify levels of antimicrobials, antivirals, oral contraceptives, and erectile dysfunction agents. Additionally, samples will be collected from individuals not on these medications to ensure quality control of the assays.
Why it matters
Potential benefit: If successful, this study could enhance the reliability of drug concentration measurements, leading to better patient management and treatment outcomes.
How similar studies have gone: While this approach is essential for ensuring assay accuracy, similar studies have shown varying degrees of success in validating drug measurement methods.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 18 years of age Exclusion Criteria: * Unable to give informed consent
Where it's running
-
Royal Liverpool University Hospital
Liverpool, United Kingdom Recruiting
Study contacts
- Principal investigator: Saye Khoo — University of Liverpool
- Study coordinator: Helen Reynolds
- Email: TherEx-trials@liverpool.ac.uk
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.