Validation of a new method for safely suctioning sputum in comatose patients
Verification of the Effect of Intermittent Negative Pressure Sputum Suction Through Oral Pharyngeal Ventilation Tube in Comatose Patients
This study is testing two different ways to safely clear mucus from the airways of comatose patients to see which method is better for their comfort and safety.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 900 (estimated) |
| Ages | 20 Years to 90 Years |
| Sex | All |
| Sponsor | Affiliated Hospital of Nantong University Academic / other |
| Locations | 1 site (Nantong, Jiangsu) |
| Trial ID | NCT06508008 on ClinicalTrials.gov |
What this trial studies
This study involves 600 comatose patients in a hospital in China, who are randomly assigned to two groups to compare different sputum suction methods. Group A will use intermittent negative pressure suction through oral and pharyngeal ventilation, while Group B will use continuous negative pressure suction through standard oral and nasal suction. The research aims to evaluate the effectiveness, safety, and patient comfort associated with these suction techniques, as well as to determine the best practices for oropharyngeal ventilation tube placement. Key indicators such as blood oxygen saturation and respiratory distress will be monitored to assess the outcomes of the interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are comatose patients diagnosed with stroke.
Not a fit: Patients with multiple organ failure or multiple organ bleeding are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the safety and effectiveness of sputum suction in critically ill patients, enhancing their overall respiratory care.
How similar studies have performed: While similar studies have explored sputum suction techniques, this specific approach and validation are novel and have not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Clinical diagnosis of stroke; 2. Clinical diagnosis of comatose; Exclusion Criteria: * 1\. Clinical diagnosis of multiple organ failure; 2. Clinical diagnosis of multiple organ bleeding;
Where this trial is running
Nantong, Jiangsu
- Affiliated Hospital of Nantong University — Nantong, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Honglei Wu, MS
- Email: wu_honglei@163.com
- Phone: +8613862749927
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.