Validation of a French scale for assessing primary lateral sclerosis
Validation of the French Version of the PLSFRS Scale
This study is testing a French version of a scale to see how well it measures the abilities of people with primary lateral sclerosis to make sure it fits their needs.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Tours Academic / other |
| Locations | 7 sites (Brest and 6 other locations) |
| Trial ID | NCT06878235 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the psychometric properties of the French version of the Primary Lateral Sclerosis Functioning Rating Scale (PLSFRS) across eight ALS centers in France. It aims to enroll 80 patients diagnosed with primary lateral sclerosis (PLS) who will be assessed at three different time points using both the ALSFRS-r and PLSFRS scales. The study seeks to ensure that the PLSFRS is culturally and linguistically appropriate for the French population, thereby enhancing its utility in clinical settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with primary lateral sclerosis who can provide informed consent.
Not a fit: Patients who do not speak French or are unable to complete questionnaires will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a validated tool for better assessing the functional status of patients with primary lateral sclerosis in French-speaking populations.
How similar studies have performed: While this study focuses on validating a specific scale, similar studies have successfully validated other assessment tools for ALS, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with primary lateral sclerosis (PLS) * Age over 18 years * Informed consent signed * Patients cared in a French ALS centre Exclusion Criteria: * patients with no oral and written command of the French language * Patients unable to answer a questionnaire * Opposition to data processing
Where this trial is running
Brest and 6 other locations
- University hospital — Brest, France (Recruiting)
- University hospital — Clermont-Ferrand, France (Not_yet_recruiting)
- University hospital — Lille, France (Not_yet_recruiting)
- University hospital — Limoges, France (Not_yet_recruiting)
- University hospital — Lyon, France (Not_yet_recruiting)
- University Hospital — Nice, France (Not_yet_recruiting)
- University hospital — Tours, France (Not_yet_recruiting)
Study contacts
- Principal investigator: Philippe CORCIA, PR — University Hospital, Tours
- Study coordinator: Philippe CORCIA, Pr
- Email: philippe.corcia@univ-tours.fr
- Phone: 0247473724
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.