Validating resuscitation termination rules for cardiac arrest patients in Asia
Official title: The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries
Run by National Taiwan University Hospital · NCT05545176 · Data updated 2026-11-12
This study is testing if the rules used to decide when to stop resuscitation for cardiac arrest patients work well for people in Asia, including kids and those with different types of emergencies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 140000 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | January 1, 2007 |
| Main results expected | June 1, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | February 25, 2026 |
| Trial ID | NCT05545176 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients experiencing out-of-hospital cardiac arrest in Asian countries.
✕Probably not a fit
Patients under 18 years old or those with obvious signs of death or do-not-resuscitate orders will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to validate the effectiveness of existing termination-of-resuscitation (TOR) rules for out-of-hospital cardiac arrest (OHCA) patients in various Asian countries. It will assess whether these rules, developed in Western contexts, are applicable to the unique characteristics of Asian populations, which may differ in terms of emergency medical services and patient demographics. The study will include non-traumatic, traumatic, and pediatric OHCA patients and evaluate factors that could influence the performance of these TOR rules.
Why it matters
Potential benefit: If successful, this study could improve decision-making in emergency medical services, potentially leading to better patient outcomes in OHCA cases.
How similar studies have gone: While there have been studies on TOR rules in Western contexts, this study is novel as it seeks to validate these rules specifically for Asian populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * out of hospital cardiac arrest (OHCA) patients Exclusion Criteria: * age \<18 years * non-EMS transport to the emergency department * obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders * missing data despite meeting the inclusion criteria.
Where it's running
-
National Taiwan University
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Shu-Hsien Hsu, MPH — National Taiwan University
- Study coordinator: Shu-Hsien Hsu, MPH
- Email: pedroe929@gmail.com
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Minimal Sedation After Out-of-Hospital Cardiac Arrest
This study tests whether stopping continuous sedation right after return of circulation is as safe as keeping patients sedated in the early hours after OHCA.
-
Drone delivery of AEDs to bystanders for out-of-hospital cardiac arrest
This project will test whether drones can deliver AEDs quickly to bystanders helping someone who has a cardiac arrest outside a hospital.
-
Pre-hospital wearable cooling after out-of-hospital cardiac arrest
This pilot test tries a battery-free CarbonCool® cooling vest applied by paramedics to adults who regain a pulse after out-of-hospital cardiac arrest but remain unconscious to see if early cooling is feasible and safe.
-
Early double sequential defibrillation for cardiac arrest outside the hospital
We test whether using two defibrillators in quick succession after the first failed shock helps adults with out‑of‑hospital cardiac arrest and a shockable rhythm survive more often than continuing standard single shocks.
-
Prehospital access to extracorporeal cardiopulmonary resuscitation in Prague
This study is testing if a special emergency treatment called prehospital extracorporeal cardiopulmonary resuscitation (ECPR) can help people who have a cardiac arrest outside of the hospital survive better and have better brain function compared to those who only get treatment in the hospital.
-
Initial double sequential defibrillation for out-of-hospital ventricular fibrillation
This trial will test whether using two defibrillators to give double sequential shocks first improves survival for adults with out-of-hospital cardiac arrest and a shockable rhythm.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.