Vagus nerve stimulation to improve sleep in elderly patients after surgery
Transauricular Vagus Nerve Stimulation (taVNS) Improves Postoperative Sleep Disorders in Elderly Patients:a Randomized Controlled Study.
This study is testing if a new way to stimulate the vagus nerve can help older patients sleep better after having surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 164 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Beijing Tiantan Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06421051 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the use of transauricular vagus nerve stimulation to enhance postoperative sleep quality in elderly patients who have undergone elective general anesthesia. The study is designed as a prospective, randomized controlled, triple-blind trial, focusing on patients aged 65 and older. By targeting postoperative sleep disorders, which are prevalent in this age group, the trial aims to assess the efficacy of this intervention in improving overall recovery and health outcomes.
Who should consider this trial
Good fit: Ideal candidates are elderly patients aged 65 and older undergoing non-craniocerebral surgery under elective general anesthesia.
Not a fit: Patients who are expected to retain tracheal intubation after surgery or have severe cognitive impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve sleep quality and recovery in elderly patients after surgery.
How similar studies have performed: While the specific application of transauricular vagus nerve stimulation for postoperative sleep disorders in elderly patients is novel, similar approaches in other contexts have shown promise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing non-craniocerebral surgery under elective general anesthesia * Age ≥65 years old * American society of Aneshesiologists Grade I to III * Sign informed consent Exclusion Criteria: * Patients who are expected to retain tracheal intubation after surgery * Disturbance of consciousness, mental disorder, inability to cooperate * Expected survival \< 3 months * The estimated operation time is \< 2 hours * The expected postoperative hospital stay is \< 5 days
Where this trial is running
Beijing, Beijing Municipality
- Beijing Tiantan Hospital, Capital Medical University — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Ruquan Han, MD
- Email: ruquan.han@ccmu.edu.cn
- Phone: 8610-59976660
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.