Using zolmitriptane to prevent childhood migraines

Zolmitriptane as Prophylactic Therapy Childhood Migraine

Phase 4 Interventional Tanta University · NCT06089356

This study tests if zolmitriptane can help prevent migraines in children better than two other treatments, topiramate and valproate.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment90 (estimated)
Ages8 Years to 18 Years
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta, Kafrelsheikh)
Trial IDNCT06089356 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of zolmitriptane as a prophylactic treatment for childhood migraines. It involves 90 children with migraines, divided into three groups: one receiving zolmitriptane, another receiving topiramate, and the last receiving valproate. The goal is to compare the efficacy of zolmitriptane against these other treatments. The study is designed to provide insights into the best preventive options for managing migraines in children.

Who should consider this trial

Good fit: Ideal candidates for this study are children diagnosed with migraines.

Not a fit: Patients with ischemic heart disease or allergies to any of the drugs used will not benefit from this study.

Why it matters

Potential benefit: If successful, this could provide a new effective option for preventing migraines in children.

How similar studies have performed: While there have been studies on migraine treatments, the specific use of zolmitriptane as a prophylactic in children is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

children with migraine -

Exclusion Criteria:

those who suffer from ischemic heart disease , or who have allergy to any of drugs used

-

Where this trial is running

Tanta, Kafrelsheikh

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Migraine
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.