Using Zn-DDC to target cancer stem cells in multiple myeloma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the effects of Zn-DDC, also known as Imuthiol, on cancer stem cells in patients with multiple myeloma and acute leukaemia. Up to 60 bone marrow samples from myeloma patients and 10 samples from other haematological malignancies will be collected during routine clinical care. Participants will provide additional bone marrow samples for analysis, which will help assess the drug's efficacy and safety in combination with other treatments like lenalidomide and pomalidomide. The study will also collect clinical data to correlate with the laboratory findings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with haematological malignancy - either myeloma or acute leukaemia
* Patients must be 18 years or over
* Patients must be willing and able to give informed consent

Exclusion Criteria:

* Pregnant patients will not be entered

Where it's running

• The Royal Wolverhampton NHS Trust
  Wolverhampton, United Kingdom Recruiting

Study contacts

• Principal investigator: Supratik Basu — The Royal Wolverhampton NHS Trust
• Study coordinator: Supratik Basu
• Email: supratik.basu@nhs.net
• Phone: 01902307999

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.