Using zinc oxide ozonated olive oil for treating dental pulp issues in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of zinc oxide-ozonated olive oil (ZnO-OO) compared to Modified Triple Antibiotic Paste (MTAP) in treating pulp necrosis in primary molars. The research focuses on children aged 4-7 years who exhibit signs of pulp disease, aiming to preserve primary teeth and prevent complications associated with early tooth loss. The methodology includes clinical assessments and radiographic evaluations to determine the success of the treatments in promoting lesion sterilization and tissue repair.

Why it matters

Who can join: the full rules

Inclusion Criteria: 1- Cooperative patients in the age group of (4-7) years with no associated systemic illness.

2- Bilateral mandibular primary molars showing signs and symptoms of pulp necrosis or chronic pulp infection with/without hemorrhage, suppuration, or purulence.

3- Spontaneous pain or tenderness to percussion. 4- Presence of chronic apical abscess, sinus tract, or grade I mobility. 5-The tooth should be restorable. 6- Radiographic characteristics are:

1. Widening of Periodontal ligament space.
2. Radicular involvement.
3. Furcation involvement less than or equal to half of the shortest root in the vertical dimension

   \-

   Exclusion Criteria: Exclusion criteria :
   1. Physiologic root resorption is more than one-third of its length.
   2. Excessive internal resorption.
   3. Non-restorable teeth exhibiting greater than grade I mobility.
   4. Perforation into the bifurcation.
   5. Any underlying pathological lesion.
   6. Any previous history of allergy to the antibiotics used in the study. -

Where it's running

• Faculty of dentistry Tanta university
  Tanta, Gharbia Governorate, Egypt Recruiting
• Nouran Esmail Mohamed Shalaby
  Menouf, Egypt Recruiting

Study contacts

• Principal investigator: Shaimaa Sh El-Desokey, Professor — Faculty of dentistry Tanta university , tanta
• Study coordinator: nouran esmail shalaby, master
• Email: PG_167682@dent.tanta.edu.eg
• Phone: +20 01018710314

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.