Using ziconotide for treating severe chronic pain not related to cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry aims to gather data on patients suffering from chronic non-cancer pain who are treated with ziconotide-based intrathecal analgesia. The study seeks to document the effectiveness and safety of ziconotide in this population, as its use has primarily been associated with cancer pain management. By collecting information from both current users of ziconotide and new candidates for treatment, the registry hopes to provide valuable insights that could guide future clinical decisions. The study addresses the gap in knowledge regarding the use of ziconotide for non-cancer pain, which is often overlooked due to a lack of comprehensive data.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18 years,
2. Chronic non-cancer pain requiring interventional techniques, and eligible to ziconotide-containing intrathecal therapy,
3. Having received information on and not opposed to data collection,

Inclusion criteria specific for the retrospective cohort:

Currently treated by ziconotide-based ITA according to SmPC whatever the duration of treatment

Inclusion criteria specific for the prospective cohort:

Naïve of ITA and candidate to ziconotide-based ITA or already treated by IT route without ziconotide, scheduled for addition of ziconotide in the pump

Exclusion Criteria:

1. Contraindication to intrathecal therapy or to ziconotide
2. Any condition that may jeopardize appropriate follow-up of the treatment
3. Patient under guardianship or deprived of liberty by a judicial or administrative decision or unable to express opposition to data collection.

Where it's running

• Clinique de la Casamance
  Aubagne, France Recruiting
• Hospices Civils de Lyon
  Bron, France Recruiting
• CHD Vendée
  La Roche-sur-Yon, France Recruiting
• CH Laon
  Laon, France Recruiting
• CHU Lille
  Lille, France Recruiting
• Clinique Mutualiste de la Porte de l'Orient
  Lorient, France Recruiting

Study contacts

• Study coordinator: CHEVALLIER Arthur
• Email: achevallier@esteve.com
• Phone: +33 (0)7 84 15 86 75

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.