Using Whole Blood for Trauma Patients in Canada

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of prehospital whole blood transfusion compared to traditional component therapy in patients with major traumatic hemorrhage. Conducted in collaboration with the SWiFT UK team, it aims to establish a protocol for administering whole blood in emergency settings, potentially improving survival rates. The trial will involve patients who have suffered traumatic injuries and require immediate blood transfusion by participating clinical teams. The study is designed to gather high-quality clinical evidence to support the use of whole blood in prehospital care across Canada.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient who has suffered a traumatic injury
* Attended by a participating Ornge AAS clinical team
* Requires prehospital blood transfusion to treat major traumatic hemorrhage

Exclusion Criteria:

* Pediatric (age \<16 or transported to pediatric trauma centre \[if age unknown\])
* No intravenous or intraosseous access (should be assessed prior to opening box)
* Knowledge that patient will object to being given blood transfusion for any reasons
* Blood already administered on-scene, prior to arrival of the participating Ornge AAS

Where it's running

• Ornge Air Ambulance
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Brodie Nolan, MD MSc — Unity Health Toronto
• Study coordinator: SWiFT Canada
• Email: swift@unityhealth.to
• Phone: 437 778 2260

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.