Using virtual reality to treat unilateral spatial neglect after stroke
Immersive Virtual REality for Treatment of Unilateral Spatial NEglect Due to Stroke Via Eye-tracking Biofeedback (IRENE Project): a Randomized Controlled Trial
This study is testing if using virtual reality can help stroke patients with unilateral spatial neglect improve their ability to explore and interact with their surroundings.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | I.R.C.C.S. Fondazione Santa Lucia Academic / other |
| Locations | 1 site (Rome, Lazio) |
| Trial ID | NCT06264713 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of immersive virtual reality treatment for patients recovering from unilateral spatial neglect following a stroke. Participants will engage in active exercises within a virtual environment designed to enhance their exploratory functions in the affected hemispace. The study aims to compare the outcomes of this experimental group with a control group receiving sham virtual reality treatment. The approach leverages advanced technology to create personalized and safe 3D environments that simulate real-life tasks, potentially improving rehabilitation outcomes. The effectiveness will be measured using specific clinical tests and scales.
Who should consider this trial
Good fit: Ideal candidates include individuals with a recent ischemic or hemorrhagic stroke resulting in unilateral spatial neglect, who can maintain a sitting position and have no significant cognitive impairments.
Not a fit: Patients with multiple or bilateral lesions, significant visual difficulties, or severe cognitive impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly enhance recovery and functional independence for patients suffering from unilateral spatial neglect.
How similar studies have performed: Previous studies have shown promising results using virtual reality for improving spatial attention in patients with unilateral spatial neglect, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ischaemic or hemorrhagic lesion in one hemisphere only (right or left hemiplegia/hemiparesis) * Presence of unilateral spatial neglect confirmed by neuropsychological examination * Mini Mental State Examination \> 23 * The patient must be able to maintain a sitting position and rotate his head * Onset acute event no later than 180 days from the date of enrollment Exclusion Criteria: * Multiple or bilateral lesions * Presence of visual difficulties * Right neglect with associated aphasic deficit (in comprehension) * Mini Mental State Examination \< 23 * Presence of degenerative pathologies, tumors, or other comorbid pathologies * Epilepsy
Where this trial is running
Rome, Lazio
- IRCCS Santa Lucia Foundation — Rome, Lazio, Italy (Recruiting)
Study contacts
- Study coordinator: Valeria Verna, MSc
- Email: v.verna@hsantalucia.it
- Phone: 0651501907
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.