Using virtual reality to treat phantom limb pain

Immersive Healing: The Therapeutic Potential of Virtual Reality in Phantom Limb Experience

Not applicable Interventional Wake Forest University Health Sciences · NCT06077227

This study tests whether virtual reality therapy can help people with phantom limb pain after losing a limb feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorWake Forest University Health Sciences Academic / other
Locations1 site (Charlotte, North Carolina)
Trial IDNCT06077227 on ClinicalTrials.gov

What this trial studies

This study investigates the therapeutic potential of virtual reality (VR) therapy for individuals experiencing phantom limb pain (PLP) following major limb amputation. It aims to address the limitations of previous research by utilizing a larger sample size, rigorous methodology, and a standardized treatment protocol. Participants will engage in VR therapy sessions while a matched control group will be monitored for comparison. The study seeks to enhance understanding of the phantom limb experience and improve pain management strategies for amputees.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who have undergone major limb amputation and experience phantom limb pain or negative phantom sensations.

Not a fit: Patients who do not experience phantom limb pain or have active mental illnesses, neurological diseases, or cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce phantom limb pain and improve the quality of life for amputees.

How similar studies have performed: Previous studies exploring VR therapy for PLP have shown positive outcomes, but this study aims to build on those findings with a more robust methodology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* History of major limb amputation
* Age \> 18 years old
* Presence of phantom limb pain or negative phantom sensation(s)

Exclusion Criteria:

* Active mental illness, neurological disease, or cognitive impairment that would interfere with survey completion
* Those without phantom limb pain or negative phantom limb sensations
* Non-English speaking

Where this trial is running

Charlotte, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Phantom Limb Painamputeepain managementvirtual reality therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.