Using virtual reality to manage behavioral and psychological symptoms in dementia patients
Developing Immersive Gamification Technology Systems for the Management of Patients With Alzheimer's Disease With Behavioral and Psychological Symptoms of Dementia (Phase 2 Trial)
This study is testing whether virtual reality can help manage the behavioral and psychological symptoms in older adults with mild to moderate Alzheimer's disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Augmented eXperience E-health Laboratory Academic / other |
| Locations | 1 site (City Of Manila, National Capital Region) |
| Trial ID | NCT06072014 on ClinicalTrials.gov |
What this trial studies
This project aims to evaluate the effectiveness of an immersive technology system, specifically virtual reality, in managing behavioral and psychological symptoms of dementia in patients with mild to moderate Alzheimer's disease. The second phase of the study will assess the clinical effectiveness, safety, usability, and acceptability of this technology among eligible participants. The study involves patients aged 60 and older who meet specific cognitive and behavioral criteria, ensuring a targeted approach to treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 60 and older diagnosed with mild to moderate Alzheimer's disease who can walk unassisted or with minimal assistance.
Not a fit: Patients with mild cognitive impairment, other non-amnestic dementia syndromes, or significant sensory impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the management of behavioral and psychological symptoms in dementia patients, enhancing their quality of life.
How similar studies have performed: While immersive technology in dementia care is an emerging field, similar studies have shown promising results, indicating potential for success in this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 60 years old or older * Diagnosed with mild to moderate Alzheimer's dementia according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria * Montreal Cognitive Assessment-Philippines (MOCA-P) score of 10-20 inclusive * Neuropsychiatric Inventory (NPI-12) score 1-50 inclusive * Reisberg Scale Stage 4-5 inclusive * Stable dose of antidepressants for the past 6 weeks * Stable dose of antipsychotics for the past 4 weeks * Able to walk unassisted or with minimal assistance, with or without assistive device * No other explanation for condition based on reasonable clinical diagnostics Exclusion Criteria: * Have mild cognitive impairment (no dementia) * Have MOCA-P score less than 10 or more than 20 * Other non-amnestic dementia syndromes * Have receptive aphasia * Have significant visual or hearing impairment * Have an active psychiatric disorder prior to Alzheimer dementia diagnosis * Had previous episodes of seizures, diagnosis of epilepsy, or intake of antiepileptic or seizure medications * Have quadriplegia or paralysis of the dominant hand * Have a history of motion sickness * Experience claustrophobia * Have a diagnosis of a terminal illness or a life expectancy of less than one year
Where this trial is running
City Of Manila, National Capital Region
- University of the Philippines College of Allied Medical Professions Immersive Technology Laboratory — City Of Manila, National Capital Region, Philippines (Recruiting)
Study contacts
- Principal investigator: Veeda Michelle M. Anlacan, MD — University of the Philippines Manila
- Study coordinator: Roland Dominic G. Jamora, MD, PhD
- Email: rgjamora@up.edu.ph
- Phone: +639985438062
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.