Using virtual reality to improve eye coordination and focusing problems

Effectiveness of Vision Therapy in a Virtual Reality Headset

Early Phase 1 Interventional OculoMotor Technologies · NCT04691427

This study is testing whether a fun virtual reality game can help people with eye coordination and focusing problems feel better.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment50 (estimated)
Ages9 Years to 35 Years
SexAll
SponsorOculoMotor Technologies Industry-sponsored
Locations2 sites (Newark, New Jersey and 1 other locations)
Trial IDNCT04691427 on ClinicalTrials.gov

What this trial studies

This research evaluates the effectiveness of virtual reality vision therapy, specifically designed to treat convergence insufficiency. Participants will engage in a custom video game using a virtual reality headset, which incorporates eye-tracking technology to objectively monitor their eye muscle responses and symptoms of eyestrain. The study aims to assess improvements in eye coordination and focusing abilities before and after the intervention. By utilizing an entertainment device, the study seeks to provide a novel approach to vision therapy.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 9 years and older with a CISS score of 16 or higher and good visual acuity.

Not a fit: Patients with certain ocular or systemic conditions, such as strabismus or diseases affecting ocular motility, may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could significantly enhance the treatment of eye coordination issues, leading to improved quality of life for patients with convergence insufficiency.

How similar studies have performed: While the use of virtual reality in therapy is gaining traction, this specific application for convergence insufficiency is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 9 years and older
* CISS score ≥ 16
* Best-corrected distance visual acuity of 20/25 or better in each eye
* Random dot stereopsis appreciation of 500 seconds of arc or better
* Parent or subject understands the protocol and is willing to enroll in the study

Exclusion Criteria:

* Constant strabismus at distance or near
* Vertical heterophoria ≥ 2 ∆ at distance or near
* ≥ 2 line interocular difference in best-corrected visual acuity
* Near point of accommodation \> 20 cm in either eye as measured by push-up method
* Manifest or latent nystagmus
* Non-strabismic binocular vision and accommodative disorders associated with known disease of the brain
* Diseases known to affect accommodation, vergence, or ocular motility such as multiple sclerosis, Graves orbitopathy, myasthenia gravis, diabetes mellitus, Parkinson disease
* Any ocular or systemic medication known to affect accommodation or vergence such as anti-anxiety agents (e.g., Librium or Valium), anti-arrhythmic agents (e.g., Cifenline, Cibenzoline), anti-cholinergics, bladder spasmolytic drugs (e.g., Propiverine), hydroxychloroquine, chloroquine, phenothiazines (e.g., Compazine, Mellaril, Thorazine), tricyclic antidepressants (e.g., Elavil, Nortriptyline, Tofranil)
* Inability to comprehend and/or perform any study-related test or procedure

Where this trial is running

Newark, New Jersey and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Convergence Insufficiency
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.