Using virtual reality for knee osteoarthritis physiotherapy

A Randomised Feasibility Study to Evaluate Home-based Personalised Virtual Reality Physiotherapy Rehabilitation Compared to Usual Care in the Treatment of Pain for People with Knee Osteoarthritis

Not applicable Interventional Cardiff University · NCT06639867

This study is testing whether using virtual reality games for home physiotherapy can help people with knee osteoarthritis improve their knee function and reduce pain compared to regular physiotherapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages45 Years and up
SexAll
SponsorCardiff University Academic / other
Locations2 sites (Cardiff and 1 other locations)
Trial IDNCT06639867 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility of a non-immersive virtual reality system designed to assist individuals with knee osteoarthritis through home-based physiotherapy. Participants will use sensors to control an animated character in games that mimic traditional physiotherapy exercises, aiming to improve their knee function and reduce pain. The intervention will be compared to standard physiotherapy care, with both groups monitored over a 12-week period. The study focuses on assessing recruitment feasibility, participant engagement, and the effectiveness of the intervention in a larger future trial.

Who should consider this trial

Good fit: Ideal candidates are adults aged 45 or older with a clinical diagnosis of knee osteoarthritis and self-reported pain.

Not a fit: Patients with knee pain from other sources, recent knee surgery, or contraindications to exercise may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a novel and engaging way for patients to manage knee osteoarthritis pain and improve their mobility from the comfort of their homes.

How similar studies have performed: While the use of virtual reality in physiotherapy is emerging, this specific approach is novel and has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 45 or older years
* Clinical diagnosis of knee osteoarthritis
* Referred for physiotherapy for clinically diagnosed knee osteoarthritis pain
* Activity related joint pain
* Self-reported knee pain on most days for the past 3 months
* Average pain severity in the past week of 4 or greater on a 10-point numeric rating scale
* Able to understand written and spoken English
* Able to provide written informed consent

Exclusion Criteria:

* Where knee is not identified by the participant as the main source of pain (e.g. comorbid painful conditions, widespread pain).
* Contraindication to exercise
* Pain caused by malignancy, fractures, or inflammatory arthritis
* Has received surgery for their knee pain in the last 12 months
* Has commenced another new treatment for knee pain, including intra-articular injection, during the preceding 12 weeks
* Concurrent ongoing treatment by physiotherapy other than the trial interventions
* Previous knee arthroplasty in either knee
* Unable to walk without a walking aid
* Unable or unwilling to engage in either active or control intervention

Where this trial is running

Cardiff and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee OsteoarthritisVirtual realityPhysiotherapyHome-based physiotherapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.