Using virtual planning to guide jaw tumor removal and reconstruction with bone from the hip

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center interventional protocol will enroll 10 patients with biopsy-confirmed ameloblastoma requiring segmental mandibular resection that spares the condyle and will use preoperative CT-based virtual surgical planning (VSP) to create resection and reconstruction guides. All defects will be reconstructed using bicortical anterior iliac crest bone blocks planned in a 1:1 cortical-to-cancellous ratio and positioned with the VSP guides. Resected specimens will undergo three-dimensional radiographic analysis to measure how closely the surgical result matches the VSP and histopathological analysis to confirm margin status. Outcomes will emphasize VSP accuracy, radiographic safety margins, and early indicators of recurrence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with histologically confirmed ameloblastoma using a preoperative biopsy.
2. Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.

Exclusion Criteria

1. Patients with lateral segmental mandibular defect involving the condyle.
2. Patients with an active infection at the site of resection.
3. Patients with recurrent lesion after resection.

Where it's running

• Faculty of Dentistry, Alexandria University
  Alexandria, Alexandria Governorate, Egypt Recruiting

Study contacts

• Principal investigator: yehia A El-Mahallawy, PhD — Faculty of Dentistry, Alexandria University, Alexandria, Alexandria
• Study coordinator: yehia A El-Mahallawy., PhD
• Email: yehia.el-mahallawy@alexu.edu.eg
• Phone: +201007217014.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.