Using virtual mapping to improve catheter ablation for atrial fibrillation

Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Virtual Rotor Mapping and Catheter Ablation

NA · Yonsei University · NCT02558699

This study is testing if using a special 3D mapping technique can make catheter ablation more effective for people with paroxysmal atrial fibrillation by helping doctors target the problem areas better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment110 (estimated)
Ages19 Years to 80 Years
SexAll
SponsorYonsei University (other)
Locations1 site (Seoul)
Trial IDNCT02558699 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of virtual rotor mapping in guiding catheter ablation for patients with paroxysmal atrial fibrillation. By creating a patient-specific 3D atrial model, the researchers aim to enhance the precision of the ablation procedure and reduce recurrence rates. The study will compare outcomes from traditional circumferential pulmonary vein isolation with those from additional rotor ablation informed by the virtual mapping technique. The goal is to determine if this innovative approach leads to better clinical results.

Who should consider this trial

Good fit: Ideal candidates are patients aged 19 to 80 diagnosed with paroxysmal atrial fibrillation who have not responded adequately to anti-arrhythmic medications.

Not a fit: Patients with severe heart deformities, significant vascular disease, or those who have previously undergone catheter ablation may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the recurrence of atrial fibrillation in patients undergoing catheter ablation.

How similar studies have performed: While the use of virtual mapping in catheter ablation is an emerging field, similar studies have shown promising results in improving outcomes for atrial fibrillation treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* AF patient age 19\~80
* Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy.

Exclusion Criteria:

* AF patients who have severe heart deformations or vascular disease.
* The patient who have renal disease of eGFR\<30mL/min
* The patients who had been performed catheter ablation of atrial ablation and MAZE.
* The patients who missed out to recording of 3D CT, echo and electrocardiography.
* the patient have experienced major hemorrhagic complication
* The patient have experienced ischemic cerebral infarction more 2 times
* The patient who have risk of ischemic cerebral infarction (CHA2DS2-VASc Score \>5)

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Paroxysmal Atrial Fibrillation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.