Using video therapy and financial incentives to improve treatment for latent tuberculosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a new approach that combines Video Directly Observed Therapy (vDOT) with financial incentives to enhance treatment completion rates for latent tuberculosis (LTBI). Adult participants diagnosed with LTBI will be recruited from the Baltimore City Health Department. The study aims to compare the effectiveness of vDOT alone and vDOT with financial incentives against usual care in promoting adherence to LTBI treatment. The intervention addresses barriers such as socioeconomic factors and competing health priorities that often hinder treatment completion.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years old or older,
* diagnosed with latent TB and determined to be appropriate for latent TB treatment by participants clinicians
* reside in Baltimore metro area
* speaks English or Spanish, or a language for which there is a short form available via the Johns Hopkins Medicine Institutional Review Board
* prescribed 3 months Isoniazid/Rifapentine, prescribed 3 months Isoniazid/Rifampin, or 4 months Rifampin

Exclusion Criteria:

* younger than 18 years old
* diagnosed with active TB
* prescribed an alternative treatment regimen for latent TB
* pregnant women (as determined by non-study directed clinical evaluation; BCHD performs urine pregnancy testing on women of child bearing age when indicated)
* participant's spoken language does not have a translated long or short consent form

Where it's running

• Baltimore City Health Department, and Baltimore metropolitan area clinics and health departments
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Maunank Shah, MD, PhD — Johns Hopkins University
• Study coordinator: Principal Investigator
• Email: mshah28@jhmi.edu
• Phone: 443-287-0401

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.