Using vancomycin powder to prevent infections in spine surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of intrawound vancomycin powder in reducing postoperative wound infections in patients undergoing spine surgery. Participants will be randomly assigned to receive either the vancomycin intervention or standard care without it, while both the patients and the surgeons will remain blinded to the treatment allocation. Data on patient demographics, comorbidities, and surgical details will be collected, and the incidence of infections will be monitored for 12 weeks post-surgery. The goal is to determine if local vancomycin application can significantly lower the rates of surgical site infections compared to standard practices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients requiring surgery due to any spine disease.

Exclusion Criteria:

* A previous history of infections at the spine surgical site.
* Biopsy procedure.
* Patients with a postoperative follow-up time of less than 12 weeks.
* Patients allergic to vancomycin.
* Patient is less than 18 years old.

Where it's running

• Windsor Regional Hospital - Ouellette
  Windsor, Ontario, Canada Recruiting
• Cairo University Hospitals
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Mohamed Soliman, MD — Western University
• Study coordinator: Mohamed Soliman, MSc, MD
• Email: msolim8@uwo.ca
• Phone: 17329241637

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.