Clinical trial Recruiting at 1 site Observational Ages 0 Months to 6

Using ultrasound to visualize kidney issues in children with congenital anomalies

Official title: Non-invasive Evaluation of Kidneys in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Using Ultrasound Localization Microscopy

Run by University of Erlangen-Nürnberg Medical School · NCT06921733 · Data updated 2026-11-12

This study is testing if special ultrasound techniques can help doctors see kidney problems in children with birth defects affecting their kidneys and urinary tract.

Quick facts

Study typeObservational
Ages0 Months to 6 Years
SexAll
Enrollment20 (estimated)
SponsorUniversity of Erlangen-Nürnberg Medical School
Academic / other
Locations1 site (Erlangen, Bavaria)
StatusRecruiting
StartedMay 13, 2025
Main results expectedDecember 1, 2025
Study endsDecember 1, 2027
Registry record updatedSeptember 17, 2025
Trial IDNCT06921733 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are infants and young children aged 1 month to 6 years diagnosed with congenital anomalies of the kidney and urinary tract.

Probably not a fit

Patients who do not have congenital anomalies of the kidney and urinary tract or those who cannot provide consent from a parent or legal guardian may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to non-invasively visualize kidney perfusion and microvascularization in children with congenital anomalies of the kidney and urinary tract (CAKUT) using Ultrasound Localization Microscopy (ULM) and Contrast Enhanced Ultrasound (CEUS). CAKUT affects a significant number of newborns and can lead to severe health complications, including chronic kidney failure. The study seeks to identify reliable biomarkers for assessing kidney function and damage in young patients, which are currently lacking. By improving the understanding of kidney development and damage in these patients, the study hopes to enhance clinical outcomes.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive method to better assess kidney function and predict chronic kidney injury in children with CAKUT.

How similar studies have gone: While there is ongoing research in the field of kidney imaging, this specific approach using ULM and CEUS in CAKUT patients is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Minimum Age 1 Month Maximum Age 6 Years Indication for MAG3 Scintigraphy of the Kidney Congenital Anomalies of the Kidney and Urinary Tract Obstruction Diagnosis Availability of the qualified examiner Consent of the parents/legal guardians

Exclusion Criteria:

Lack of consent of at least one parent

Where it's running

  • FAU Erlangen-Nuernberg,
    Erlangen, Bavaria, Germany
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.