Using ultrasound to treat recurrent thyroid cancer

Ultrasound-guided Thermal Ablation for Recurrent Thyroid Cancer: A Multicenter Study

Observational Chinese PLA General Hospital · NCT06733766

This study is testing if using ultrasound to heat and destroy recurrent thyroid cancer can be a safe and effective treatment for patients who have already had surgery for their thyroid cancer.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorChinese PLA General Hospital Academic / other
Locations1 site (Beijing, Beijing Municipality)
Trial IDNCT06733766 on ClinicalTrials.gov

What this trial studies

This study evaluates the long-term outcomes of ultrasound-guided thermal ablation in patients with recurrent thyroid cancer. It is a multicenter observational study that aims to predict the effectiveness and safety of this treatment approach. Patients who have previously undergone thyroidectomy and have confirmed recurrent lesions will be monitored over a follow-up period of at least 12 months to assess their outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients who have had a thyroidectomy for thyroid cancer and have pathologically confirmed recurrent lesions without distant metastases.

Not a fit: Patients with coagulation disorders or serious organ failures, as well as those with vocal cord dysfunction on the opposite side, may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a less invasive option for managing recurrent thyroid cancer, potentially improving patient outcomes.

How similar studies have performed: Other studies have shown promising results with ultrasound-guided thermal ablation for similar conditions, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patient received thyroidectomy for thyroid cancer
2. recurrent lesions were pathologically proven to be malignant by core-needle biopsy or fine needle aspiration
3. no evidence of distant metastases.
4. follow-up period ≥12 months

Exclusion Criteria:

1. coagulation disorder, serious heart, respiratory, liver, or renal failure
2. dysfunction of the vocal cord on the opposite side

Where this trial is running

Beijing, Beijing Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Recurrent Thyroid Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.