Using ultrasound to predict ICU admission for sepsis patients in the emergency department
The Use of Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department
This study tests if using an ultrasound device on sepsis patients in the emergency room can help predict if they will need to be admitted to the ICU or face other serious outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Northwell Health Academic / other |
| Locations | 1 site (Manhasset, New York) |
| Trial ID | NCT05544903 on ClinicalTrials.gov |
What this trial studies
This observational study will apply the FloPatch device to 150 patients presenting with sepsis in the emergency department before they receive fluid resuscitation. It aims to determine if the initial measurements of volume-responsiveness and the volume of fluids administered can predict outcomes such as mortality, ICU admission, or activation of a rapid response team. The study will also evaluate how fluid unresponsiveness develops during the initial resuscitation and its correlation with these outcomes.
Who should consider this trial
Good fit: Ideal candidates are emergency department patients aged 18 and older with signs of sepsis, such as low blood pressure and elevated heart rate.
Not a fit: Patients who are already intubated, ventilator-dependent, or pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve early identification and management of sepsis, potentially reducing mortality and the need for intensive care.
How similar studies have performed: Other studies have shown promise in using ultrasound for similar predictive purposes in sepsis management, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Emergency department patient * 18+ years old * Systolic blood pressure less than 100mmHg * Respiratory rate greater than 22 breaths per minutes * Temperature greater than 38 degrees Celsius or less than 36 degrees Celsius * Heart rate greater than 90 beats per minute Exclusion Criteria: * Already intubated prior to emergency department arrival * Ventilator-dependent * Patients transferred from another hospital * Pregnancy
Where this trial is running
Manhasset, New York
- North Shore University Hospital — Manhasset, New York, United States (Recruiting)
Study contacts
- Principal investigator: Allison Cohen, MD — North Shore University Hospital
- Study coordinator: Timmy Li, PhD
- Email: tli2@northwell.edu
- Phone: 516-240-3933
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.