Using ultrasound to identify and improve treatment for left ventricular hypertrophy in emergency patients
Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy
This study is testing whether using ultrasound in the emergency room can help find and improve treatment for people with high blood pressure and undiagnosed left ventricular hypertrophy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (New Haven, Connecticut) |
| Trial ID | NCT05730309 on ClinicalTrials.gov |
What this trial studies
This project aims to assess the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in emergency department patients with high blood pressure. It will utilize point-of-care ultrasound (POCUS) to detect LVH and evaluate the impact of patient education and expedited referrals on follow-up and treatment rates. The study will also create a database of ultrasound clips to aid in developing a machine learning algorithm for future LVH detection. The goal is to enhance disease prevention equity and reduce cardiovascular disease burden.
Who should consider this trial
Good fit: Ideal candidates are emergency department patients with persistently elevated blood pressure readings above 140/90 mmHg.
Not a fit: Patients with a history of left ventricular hypertrophy or active cardiac disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and treatment rates for patients with left ventricular hypertrophy, ultimately reducing cardiovascular risks.
How similar studies have performed: Other studies have shown promise in using point-of-care ultrasound for cardiovascular assessments, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Two blood pressure measurements greater than 140 mmHg systolic and greater than 90 mmHg diastolic on two separate vital sign checks obtained as part of routine ED care Exclusion Criteria: * Subjects in extremis or lacking capacity to consent * Active treatment of hypertension within the last year * History of/known left ventricular hypertrophy * Active cardiac disease under the care of a cardiologist within last year * Suspicion for hypertensive emergency by treating ED physician * Admission to the hospital
Where this trial is running
New Haven, Connecticut
- Yale New Haven Hospital — New Haven, Connecticut, United States (Recruiting)
Study contacts
- Study coordinator: Cristiana Baloescu, MD, MPH
- Email: cristiana.baloescu@yale.edu
- Phone: (203) 737-2644
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.