Using ultrasound to help wean patients off ventilators
The Predictive Value Of Heart, Lung And Diaphragm Ultrasound For Ventilator Weaning Outcome Of Surgical Intensive Care Patients
This study is testing if using ultrasound to check the diaphragm, lungs, and heart can help doctors know when patients on ventilators are ready to breathe on their own.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 190 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hanoi Medical University Academic / other |
| Locations | 1 site (Hanoi) |
| Trial ID | NCT06321848 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how a composite model of diaphragm, lung, and heart ultrasonography can predict the outcomes of weaning patients off mechanical ventilation. It will collect ultrasonic features along with clinical data from patients who have been mechanically ventilated for over 48 hours. The study will utilize multivariate logistic regression analysis to identify variables associated with weaning failure and develop a multi-indicator model to enhance predictive accuracy. Participants will undergo a spontaneous breathing trial to assess their readiness for weaning.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years who have been mechanically ventilated for more than 48 hours.
Not a fit: Patients with progressive neuromuscular diseases or those with a history of severe cardiovascular or respiratory diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve the weaning process from ventilators, potentially reducing complications and improving outcomes for critically ill patients.
How similar studies have performed: While this approach is innovative, similar studies using ultrasound for weaning have shown promising results, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 * The duration of postoperative mechanical ventilation \>= 48 hours Exclusion Criteria: * Patient had a diagnosis of progressive neuromuscular diseases * Patient had a history of cardiovascular or respiratory disease who depend on a ventilator at home (COPD, severe bronchial asthma) * Patients had thoracic surgery or mitral valve surgery.
Where this trial is running
Hanoi
- Hanoi Medical University Hospital — Hanoi, Vietnam (Recruiting)
Study contacts
- Study coordinator: Duc Tran, MD
- Email: ductran.hmu@gmail.com
- Phone: +84983817388
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.