Using ultrasound to guide nerve ablation for pain relief after knee replacement surgery

Ultra Sound Guided Genicular Nerves Cooled Radiofrequency Ablation in Total Knee Replacement Surgeries

Not applicable Interventional Ain Shams University · NCT06651762

This study tests if using ultrasound to guide a nerve treatment can help people recover better and feel less pain after knee replacement surgery compared to standard care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment66 (estimated)
Ages21 Years and up
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06651762 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of genicular nerves cooled radiofrequency ablation in improving rehabilitation outcomes for patients undergoing total knee replacement surgery. The intervention aims to reduce postoperative pain, which can hinder recovery and patient satisfaction. By utilizing ultrasound guidance, the procedure is designed to be minimally invasive with few side effects. The study will compare the outcomes of patients receiving this nerve ablation technique against those undergoing standard care.

Who should consider this trial

Good fit: Ideal candidates are individuals scheduled for unilateral total knee replacement surgery.

Not a fit: Patients with allergies to study drugs, substance abuse issues, or psychiatric diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance pain management and rehabilitation for knee replacement patients.

How similar studies have performed: While the approach is relatively novel, similar studies have shown promising results in pain management following orthopedic surgeries.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:• Undergoing a scheduled unilateral total knee replacement surgery

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Exclusion Criteria:

* • Allergy to any of the drugs used in the study

  * Alcohol or drug abuse
  * Psychiatric disease

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis of Knee
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.