Using ultrasound to guide heart procedures in patients with kidney disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of an intravascular ultrasound (IVUS)-guided approach for performing percutaneous coronary interventions (PCI) in patients suffering from chronic kidney disease (CKD). The focus is on reducing the incidence of contrast-induced nephropathy (CIN), a serious complication that can arise from traditional PCI methods that require iodine contrast. By utilizing a 'zero-contrast' strategy, the study seeks to demonstrate that IVUS can safely guide these procedures without the associated risks of contrast agents. The primary outcome will be the incidence of CIN within 72 hours post-procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 18 years old
* Indication for PCI
* Chronic kidney disease with creatinine clearance ≤ 30 mL/min/1.73m²
* Feasibility of IVUS determined by 2 trained interventional cardiologist
* Affiliated to social security

Exclusion Criteria:

* Iodine contrast injection in the previous 72 hours
* Known allergy to iodine contrast
* Permanent dialysis
* Chronic total occlusion
* Hemodynamic instability
* Legal protection
* Pregnant of breastfeeding patients
* Patients on "AME"

Where it's running

• Romain GALLET
  Créteil, France Recruiting
• Romain GALLET
  Créteil, Creteil, France Not yet recruiting

Study contacts

• Study coordinator: Romain GALLET, Pr
• Email: romain.gallet@aphp.fr
• Phone: 01 49 81 21 11

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.