Using ultrasound to diagnose subcutaneous nodules

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of ultrasonography as a non-invasive imaging technique for diagnosing subcutaneous nodules. Patients presenting with these nodules and requiring skin biopsies are recruited to undergo ultrasound examinations prior to their biopsies. The ultrasonographic characteristics of the nodules are then compared with the pathological results from the biopsies to assess the diagnostic accuracy of ultrasound in differentiating various conditions associated with skin nodules. This approach aims to improve the understanding and classification of panniculitis and related disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 years and older who presented with subcutaneous nodules
* Indicated for pathological examination for disease diagnosis.
* Patients with subcutaneous nodules located in areas where a tissue sample can be taken down to the fat layer.
* Patients who agree to participate in the project by signing the consent form.

Exclusion Criteria:

* Presence of inflammation or other tumors that can mimic panniculitis, such as painful lipomas, cellulitis, and leg interstitial edema.
* Patients with diseases that significantly alter the structure of the skin or subcutaneous tissue, such as scleroderma or severe edema.
* A history of previous treatments in the area of the subcutaneous mass (e.g., surgery, radiation therapy, or high-dose steroid treatment) that may interfere with ultrasound results.
* Patients with lesions on the head or mucous membranes of the body.
* Pregnant or breastfeeding patients.
* Presence of wounds or open sores in the area to be examined with ultrasound.
* A history of coagulopathy (blood clotting disorders).
* Patients with metal implants in the area of interest that may interfere with ultrasound imaging.
* Participants who refuse or withdraw from the study.

Where it's running

• Ramathibodi Hospital
  Bangkok, Ratchathewi, Thailand Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.