Using ultrasound to assess blood flow after skull surgery
A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty
RenJi Hospital · NCT06642532
This study is testing how blood flow in the brain changes before and after skull surgery using ultrasound to help patients with cranial defects.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | RenJi Hospital (other) |
| Locations | 2 sites (Shanghai, Shanghai Municipality and 1 other locations) |
| Trial ID | NCT06642532 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates cerebral blood flow in patients undergoing cranioplasty with polyetheretherketone. It utilizes transcranial Doppler ultrasound to measure hemodynamic parameters before and after the surgery. The study collects data on various arteries to understand the impact of the cranioplasty on cerebral circulation. The goal is to enhance the understanding of blood flow dynamics in patients with cranial defects treated with this material.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are scheduled for polyetheretherketone cranioplasty and have an incomplete cranial bone in the lateral temporal window.
Not a fit: Patients with intact cranial bone in the temporal region, despite being proposed for cranioplasty, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve postoperative care and outcomes for patients undergoing cranioplasty.
How similar studies have performed: While the use of transcranial Doppler ultrasound in similar contexts has been explored, this specific application in conjunction with polyetheretherketone cranioplasty is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age of 18 years or older; 2. Proposed polyetheretherketone cranioplasty; 3. Incomplete cranial bone in the lateral temporal window; 4. Signed informed consent for surgery and informed consent for research. Exclusion Criteria: 1)Although cranioplasty is proposed, the cranial bone in the temporal region is intact.
Where this trial is running
Shanghai, Shanghai Municipality and 1 other locations
- Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University — Shanghai, Shanghai Municipality, China (RECRUITING)
- Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University — Shanghai, Shanghai Municipality, China (RECRUITING)
Study contacts
- Study coordinator: Junfeng Feng
- Email: fengjfmail@163.com
- Phone: 13611860825
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cranial Defect, TCD